|Table of Contents|

Analysis of related risk factors and establishment of prediction model for postoperative hypoalbuminemia in patients with gastrointestinal tumors

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2024 14
Page:
2579-2585
Research Field:
Publishing date:

Info

Title:
Analysis of related risk factors and establishment of prediction model for postoperative hypoalbuminemia in patients with gastrointestinal tumors
Author(s):
LI Zhuang1; WANG Shanshan2; DING Lirong1; SU Zhen1; LIU Hailin1; TAO Guoquan1; ZHANG Zhijie1
1.Department of Anesthesiology,the Affiliated Huai'an No.1 People's Hospital of Nanjing Medical University,Jiangsu Huai'an 223300,China;2.Department of Anesthesiology,the Fifth People's Hospital of Huai'an,Jiangsu Huai'an 223300,China.
Keywords:
gastrointestinal neoplasms; hypoalbuminemia; postoperative complications; risk factors; Nomograms
PACS:
R735.3
DOI:
10.3969/j.issn.1672-4992.2024.14.015
Abstract:
Objective:To identify the perioperative risk factors for hypoalbuminemia after gastrointestinal tumor surgery and to establish a predictive model.Methods:A retrospective analysis was conducted on the clinical data of 244 patients who underwent radical resection of gastrointestinal tumors at our hospital between December 2022 and June 2023.Logistic regression analysis was used to conduct univariate and multivariate analysis to isolate independent risk factors for postoperative hypoalbuminemia.A Nomogram prediction model was established to evaluate its prognostic efficacy.Results:Postoperative hypoalbuminemia was observed in 125 patients (54.8%).Multivariate Logistic regression analysis identified several independent risk factors:Preoperative albumin level (OR 0.70,P＜0.01),BMI (OR 0.79,P＜0.01),intraoperative hormone (OR 0.92,P＜0.01),albumin dosage (OR 0.72,P＜0.01),blood glucose at the end of operation (OR 1.54,P＜0.01) and combined epidural anesthesia (OR 0.38,P＜0.05).The predictive model's area under the ROC curve was 0.848(95%CI 0.800~0.896),indicating a highpredictive value.Conclusion:The preoperative albumin level,BMI,intraoperative hormone and albumin use,blood glucose at the end of surgery and combined epidural anesthesia are significant independent risk factors of postoperative hypoalbuminemia.The Nomogram prediction model based on the above variables has high prediction efficiency and can serve as an effective tool for clinical decision-making.

References:

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Memo

Memo:
National Natural Science Foundation of China(No.81773538);国家自然科学基金（编号：81773538）
Last Update: 1900-01-01