|Table of Contents|

Research progress on the function and role of ceruloplasmin in tumor occurrence and development

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2023 23
Page:
4440-4444
Research Field:
Publishing date:

Info

Title:
Research progress on the function and role of ceruloplasmin in tumor occurrence and development
Author(s):
XIE Qibin; HONG Liu; YANG Wanli; FAN Aqiang
Department of Digestive Surgery,Xijing Hospital,Air Force Medical University,Shaanxi Xi'an 710032,China.
Keywords:
ceruloplasmin; copper transportation; oxidative stress; tumor
PACS:
R730.231
DOI:
10.3969/j.issn.1672-4992.2023.23.028
Abstract:
Ceruloplasmin(Cp) is a copper-containing α-2 globulin,a member of the multicopper oxidase family,which is mainly distributed in human plasma.The functions of Cp mainly include copper transport,iron homeostasis regulation,oxidase activities,antioxidant activities,acute-phase protein,which play an important role in the occurrence and development of many diseases.With the continuous development of scientific research,the roles of Cp in various tumors has been revealed,suggesting its potential clinical value.In this review,the research progress of Cp in tumorigeneses and development in recent years will be reviewed,so as to provide certain reference for subsequent clinical and basic scientific research.

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Memo

Memo:
National Natural Science Foundation of China（No.82073210）;国家自然科学基金课题（编号：82073210）；肿瘤生物学国家重点实验室（第四军医大学）课题（编号：CBSKL2022ZZ37）
Last Update: 2023-10-31