|Table of Contents|

Recent progress of non-coding RNAs regulate tumour genesis of non-small cell lung cancer through modulation of ferroptosis

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2023 21
Page:
4092-4096
Research Field:
Publishing date:

Info

Title:
Recent progress of non-coding RNAs regulate tumour genesis of non-small cell lung cancer through modulation of ferroptosis
Author(s):
ZHANG Xiaojie1; PAN Defu2; ZHU Xiaomin1; WANG Yumin3
1.Department of Respiratory and Critical Care Medicine,the Affiliated Hospital of Chifeng University,Inner Mongolia Chifeng 024000,China;2.31438 Troops of the Chinese People's Liberation Army,Liaoning Shenyang 110000,China;3.Department of Respiratory and Critical Care Medicine,Aerospace Center Hospital,Peking University Aerospace School of Clinical Medicine,Beijing 100049,China.
Keywords:
NSCLC; ferroptosis; non-coding RNAs
PACS:
R734.2
DOI:
10.3969/j.issn.1672-4992.2023.21.036
Abstract:
Accumulating evidence have shown that non-coding RNAs(ncRNAs),such as microRNAs(miRNAs),long non-coding RNAs(lncRNAs),and circular RNAs(circRNAs) have been found to play an important role in the initiation and development of non-small cell lung cancer(NSCLC) through modulation of ferroptosis,an iron-dependent form of regulated cell death(RCD),attributed to the accumulation of lipid hydroperoxides and redox imbalance.Despite these advances,a systematical review insight into the role of ncRNAs modulate ferroptosis in NSCLC is still lacking till date.The current review briefly introduces ferroptosis,and then provided the recent progress in elucidating the molecular mechanism of ncRNAs modulate ferroptosis in NSCLC,hoping to uncover the molecular mechanism by which ncRNA sengages in the pathogenesis of NSCLC through modulatig ferroptosis.

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Memo

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北京市海淀区卫生健康发展科研培育计划(编号：HP2021-19-50701)；中国航天科工集团课题(编号：2020-LCYL-009); 航天中心医院院级课题(编号：YN202104)
Last Update: 2023-09-28