|Table of Contents|

The value of PSL technology in the evaluation of left ventricular work in multiple myeloma patients

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2023 21
Page:
4003-4007
Research Field:
Publishing date:

Info

Title:
The value of PSL technology in the evaluation of left ventricular work in multiple myeloma patients
Author(s):
LIU Juan1; XU Jun2; JU Ping2; SUN Hongguang2; LIU Chen3
1.Department of Ultrasound，the Fourth People's Hospital of Lianyungang，Jiangsu Lianyungang 222023，China;2.Department of Ultrasound，Medical Imaging Center,Affiliated Hospital of Yangzhou University，Jiangsu Yangzhou 225001，China;3.Department of Cardiology,Affiliated Hospital of Yangzhou University，Jiangsu Yangzhou 225001，China.
Keywords:
echocardiography; multiple myeloma; pressure strain loop; left ventricular function; peak strain dispersion
PACS:
R733.3
DOI:
10.3969/j.issn.1672-4992.2023.21.018
Abstract:
Objective:To study the early left ventricular work in multiple myeloma patients with normal left ventricular ejection fraction（LVEF) by PSL technology.Methods:A total of 52 patients with multiple myeloma diagnosed in the department of hematology from June 2021 to July 2022 and 32 age-and gender-matched healthy controls were prospectively enrolled in the study.Conventional echocardiography was performed and STE was used to analyze peak strain dispersion（PSD) and global longitudinal strain（GLS).After inputting blood pressure，the software automatically analyzed the global work index（GWI)，global constructive work（GCW)，global waste work（GWW)，global work efficiency（GWE).The differences and correlations of all the measured parameters were statistically analyzed between the two groups.Results:The E/A ratio，IVS e '，LVSW e' in the MM group were significantly lower than those in the control group（Z/t=3.725，2.822，2.816)，while A value，E/e' was significantly higher than that in the control group（Z/t=2.876,5.486)，with statistical significance（P<0.05).The GLS absolute value，GWI，and GWE of the MM group were all lower than those of the control group（U=360.000，470.000，118.000)，while GWW and PSD were higher than those of the control group（U=137.000，381.500)，with statistical significance（P<0.05).GLS absolute value，GWI，GCW，GWE were positively correlated with LVEF（r=0.716,0.522，0.503，0.335,P<0.05).GWW and PSD were negatively correlated with LVEF（r=-0.236，-0.543，P<0.05).The repeatability test showed good operability and repeatability.Conclusion:PSL technology can quantitatively evaluate the left ventricular work and left ventricular systolic dyssynchrony in patients with early multiple myeloma，and can detect the left ventricular systolic function injury earlier than conventional echocardiography，which can provide clinical reference.

References:

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Memo

Memo:
江苏省扬州市科技计划基金（编号：YZ2022079）
Last Update: 2023-09-28