|Table of Contents|

Pregnancy management of patients with chronic granulocyte leukemia

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2023 16
Page:
3122-3126
Research Field:
Publishing date:

Info

Title:
Pregnancy management of patients with chronic granulocyte leukemia
Author(s):
PEI JiaojiaoXIE JiangyanHUANG Chaolin
Department of Obstetrics and Gynecology,the First Affiliated Hospital of Chengdu Medical School,Sichuan Chengdu 610500,China.
Keywords:
leukemiamyelogenouschronicBCR-ABL positivepregnancydisease management
PACS:
R733.7
DOI:
10.3969/j.issn.1672-4992.2023.16.035
Abstract:
As the significant improvement of the survival rate of patients with chronic myeloid leukemia,more and more people ask to solve fertility problems,which challenges the management of pregnant patients with chronic myeloid leukemia.Although there is no doubt about the safety and efficacy of tyrosine kinase inhibitor in the clinical treatment of patients with chronic myeloid leukemia,the effect of tyrosine kinase inhibitor on fertility and teratogenicity limits its application in pregnancy.Treatment methods such as leukocyte separation,interferon,and hydroxyurea have become other choices for patients with chronic myeloid leukemia during pregnancy.While choosing the best time for pregnancy,we should follow the principles of individualization and multidisciplinary cooperation,and fully assess the harm of continued treatment to the fetus and the risk of treatment interruption to the mother.The purpose of this review is to provide suggestions for pregnancy management in patients with chronic myeloid leukemia.

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Memo

Memo:
四川省医学青年创新科研课题计划(编号:Q20075);四川省成都市卫生健康委员会科研项目(编号:2022657)
Last Update: 1900-01-01