[1] SUNG H,FERLAY J,SIEGEL RL,et al.Global cancer statistics 2020:GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries [J].CA Cancer J Clin,2021,71(3):209-249.
[2] KORBECKI J,OLBROMSKI M,DZIEGIEL P.CCL18 in the progression of cancer [J].Int J Mol Sci,2020,21(21):7955.
[3] ANDREF E,FOULKES MA.A phased approach to clinical testing:criteria for progressing from phase I to phase II to phase III studies [J].Dev Biol Stand,1998,95:57-60.
[4] HANAHAN D,WEINBERG RA.Hallmarks of cancer:the next generation [J].Cell,2011,144(5):646-674.
[5] MULLER-QUERNHEIM UC,POTTHAST L,MULLER-QUERNHEIM J,et al.Tumor-cell co-culture induced alternative activation of macrophages is modulated by interferons in vitro [J].J Interferon Cytokine Res,2012,32(4):169-177.
[6] BALKWILL FR.The chemokine system and cancer [J].J Pathol,2012,226(2):148-157.
[7] SHARMA I,SINGH A,SHARMA KCH,et al.Gene expression profiling of chemokines and their receptors in low and high grade astrocytoma [J].Asian Pac J Cancer Prev,2017,18(5):1307-1313.
[8] MA L,WANG H,LI Z,et al.Chemokine (C-C motif) ligand 18 is highly expressed in glioma tissues and promotes invasion of glioblastoma cells [J].J Cancer Res Ther,2019,15(2):358-364.
[9]MUHAMMAD JS,MANZOOR S,CUI ZG,et al.DNA methylation-mediated overexpression of CXCL1 in helicobacter pylori-induced gastric cancer:In silico-and in vitro-based identification of a potential biomarker for carcinogenesis [J].Int J Mol Sci,2023,24(1):795.
[10]YAN R,LI J,XIAO Z,et al.DCLK1 suppresses tumor-specific cytotoxic T lymphocyte function through recruitment of MDSCs via the CXCL1-CXCR2 axis [J].Cell Mol Gastroenterol Hepatol,2023,15(2):463-485.
[11]BIANCHI A,DE CASTRO SILVA I,DESHPANDE NU,et al.Cell-autonomous Cxcl1 sustains tolerogenic circuitries and stromal inflammation via neutrophil-derived TNF in pancreatic cancer [J].Cancer Discov,2023,22:CD-22-1046.
[12]MOTYKA J,GACUTA E,KICMAN A,et al.Plasma levels of CXC motif chemokine 1 (CXCL1) and chemokine 8 (CXCL8) as diagnostic biomarkers in luminal A and B breast cancer [J].J Clin Med,2022,11(22):6694.
[13]ZHANG J,HOU W,ZUO J,et al.CXCL2 acts as a prognostic biomarker and associated with immune infiltrates in stomach adenocarcinoma [J].Medicine (Baltimore),2022,101(42):e31096.
[14]HE X,WANG L,LI H,et al.CSF2 upregulates CXCL3 expression in adipocytes to promote metastasis of breast cancer via the FAK signaling pathway [J].J Mol Cell Biol,2023:mjad025.
[15]SU P,JIANG L,ZHANG Y,et al.Crosstalk between tumor-associated macrophages and tumor cells promotes chemoresistance via CXCL5/PI3K/AKT/mTOR pathway in gastric cancer [J].Cancer Cell Int,2022,22(1):290.
[16]ZHAO J,OU B,HAN D,et al.Tumor-derived CXCL5 promotes human colorectal cancer metastasis through activation of the ERK/Elk-1/Snail and AKT/GSK3β/β-catenin pathways [J].Mol Cancer,2017,16(1):70.
[17]JING Y,WANG F,ZHANG K,et al.Comprehensive analysis of prognostic value and immune infiltration of CXC chemokines in pancreatic cancer [J].BMC Med Genomics,2022,15(1):96.
[18]WANG YH,SHEN CY,LIN SC,et al.Monocytes secrete CXCL7 to promote breast cancer progression [J].Cell Death Dis,2021,12(12):1090.
[19]LIN C,HE H,LIU H,et al.Tumour-associated macrophages-derived CXCL8 determines immune evasion through autonomous PD-L1 expression in gastric cancer [J].Gut,2019,68(10):1764-1773.
[20]AWWAD O,COPERCHINI F,PIGNATTI P,et al.The AMPK-activator AICAR in thyroid cancer:effects on CXCL8 secretion and on CXCL8-induced neoplastic cell migration [J].J Endocrinol Invest,2018,41(11):1275-1282.
[21]PAUSCH TM,AUE E,WIRSIK NM,et al.Metastasis-associated fibroblasts promote angiogenesis in metastasized pancreatic cancer via the CXCL8 and the CCL2 axes [J].Sci Rep,2020,10(1):5420.
[22]ZHOU C,HE X,TONG C,et al.Cancer-associated adipocytes promote the invasion and metastasis in breast cancer through LIF/CXCLs positive feedback loop [J].Int J Biol Sci,2022,18(4):1363-1380.
[23]WU L,SUN S,QU F,et al.CXCL9 influences the tumor immune microenvironment by stimulating JAK/STAT pathway in triple-negative breast cancer [J].Cancer Immunol Immunother,2022,72:1479-1492.
[24]SHANG S,YANG YW,CHEN F,et al.TRIB3 reduces CD8+ T cell infiltration and induces immune evasion by repressing the STAT1-CXCL10 axis in colorectal cancer [J].Sci Transl Med,2022,14(626):eabf0992.
[25]ZHANG X,HUANG J,WANG J,et al.Circ_0001667 accelerates breast cancer proliferation and angiogenesis through regulating CXCL10 expression by sponging miR-6838-5p [J].Thorac Cancer,2023,14(10):881-892.
[26]MU L,HU S,LI G,et al.Characterization of the prognostic values of CXCL family in epstein-barr virus associated gastric cancer [J].Oxid Med Cell Longev,2022,2022:2218140.
[27]WANG YC,LU S,ZHOU XJ,et al.miR-1273h-5p suppresses CXCL12 expression and inhibits gastric cancer cell invasion and metastasis [J].Open Med (Wars),2022,17(1):930-946.
[28]ZHENG X,RUI S,WANG XF,et al.circPVT1 regulates medullary thyroid cancer growth and metastasis by targeting miR-455-5p to activate CXCL12/CXCR4 signaling [J].J Exp Clin Cancer Res,2021,40(1):157.
[29]SLEIGHTHOLM RL,NEILSEN BK,LI J,et al.Emerging roles of the CXCL12/CXCR4 axis in pancreatic cancer progression and therapy[J].Pharmacol Ther,2017,179:158-170.
[30]HAYASAKA H,YOSHIDA J,KURODA Y,et al.CXCL12 promotes CCR7 ligand-mediated breast cancer cell invasion and migration toward lymphatic vessels [J].Cancer Sci,2022,113(4):1338-1351.
[31]LI Y,GUO XB,WEI YH,et al.Serum CXCL13 and PECAM-1 can be used as diagnostic and prognostic markers in elderly patients with gastric cancer [J].Clin Transl Oncol,2021,23(1):130-138.
[32]WANG Z,LIU W,WANG C,et al.miR-873-5p inhibits cell migration and invasion of papillary thyroid cancer via regulation of CXCL16 [J].Onco Targets Ther,2020,13:1037-1046.
[33]COPERCHINI F,GRECO A,CROCE L,et al.Vitamin D reduces thyroid cancer cells migration independently from the modulation of CCL2 and CXCL8 chemokines secretion [J].Front Endocrinol (Lausanne),2022,13:876397.
[34]LI W,CHEN F,GAO H,et al.Cytokine concentration in peripheral blood of patients with colorectal cancer [J].Front Immunol,2023,14:1175513.
[35]YOU D,KIM H,JEONG Y,et al.Chemokine (C-C motif) ligand 2 is regulated through the EGFR/Src pathway in HER2-positive breast cancer cells [J].Anticancer Res,2023,43(3):1079-1089.
[36]SHENG D,MA W,ZHANG R,et al.CCL3 enhances docetaxel chemosensitivity in breast cancer by triggering proinflammatory macrophage polarization [J].J Immunother Cancer,2022,10(5):e003793.
[37]QIU J,XU L,ZENG X,et al.CCL5 mediates breast cancer metastasis and prognosis through CCR5/Treg cells [J].Front Oncol,2022,12:972383.
[38]HUANG FJ,ZHOU XY,YE L,et al.Follicular thyroid carcinoma but not adenoma recruits tumor-associated macrophages by releasing CCL15[J].BMC Cancer,2016,16:98.
[39]CHEN J,YAO Y,GONG C,et al.CCL18 from tumor-associated macrophages promotes breast cancer metastasis via PITPNM3 [J].Cancer Cell,2011,19(4):541-555.
[40]ZHANG B,YIN C,LI H,et al.Nir1 promotes invasion of breast cancer cells by binding to chemokine (C-C motif) ligand 18 through the PI3K/Akt/GSK3β/Snail signalling pathway [J].Eur J Cancer,2013,49(18):3900-3913.
[41]LIN L,CHEN YS,YAO YD,et al.CCL18 from tumor-associated macrophages promotes angiogenesis in breast cancer [J].Oncotarget,2015,6(33):34758-34773.
[42]LI HY,CUI XY,WU W,et al.Pyk2 and Src mediate signaling to CCL18-induced breast cancer metastasis [J].J Cell Biochem,2014,115(3):596-603.
[43]NIE Y,CHEN J,HUANG D,et al.Tumor-associated macrophages promote malignant progression of breast phyllodes tumors by inducing myofibroblast differentiation [J].Cancer Res,2017,77(13):3605-3618.
[44]ZHAO C,ZHENG S,YAN Z,et al.CCL18 promotes the invasion and metastasis of breast cancer through Annexin A2 [J].Oncol Rep,2020,43(2):571-580.
[45]SU S,LIAO J,LIU J,et al.Blocking the recruitment of naive CD4+ T cells reverses immunosuppression in breast cancer [J].Cell Res,2017,27(4):461-482.
[46]LIU Y,ZHENG H,LI Q,et al.Discovery of CCL18 antagonist blocking breast cancer metastasis [J].Clin Exp Metastasis,2019,36(3):243-255.
[47]ZENG W,CHANG H,MA M,et al.CCL20/CCR6 promotes the invasion and migration of thyroid cancer cells via NF-kappa B signaling-induced MMP-3 production [J].Exp Mol Pathol,2014,97(1):184-190.
[48]LIU B,JIA Y,MA J,et al.Tumor-associated macrophage-derived CCL20 enhances the growth and metastasis of pancreatic cancer [J].Acta Biochim Biophys Sin (Shanghai),2016,48(12):1067-1074.
[49]ZHANG Z,SUN T,CHEN Y,et al.CCL25/CCR9 signal promotes migration and invasion in hepatocellular and breast cancer cell lines [J].DNA Cell Biol,2016,35(7):348-357.
[50]HIESHIMA K,IMAI T,BABA M,et al.A novel human CC chemokine PARC that is most homologous to macrophage-inflammatory protein-1 alpha/LD78 alpha and chemotactic for T lymphocytes,but not for monocytes[J].J Immunol,1997,159(3):1140-1149.
[51]GUAN P,BURGHES AH,CUNNINGHAM A,et al.Genomic organization and biological characterization of the novel human CC chemokine DC-CK-1/PARC/MIP-4/SCYA18 [J].Genomics,1999,56(3):296-302.
[52]KODELJA V,MULLER C,POLITZ O,et al.Alternative macrophage activation-associated CC-chemokine-1,a novel structural homologue of macrophage inflammatory protein-1 alpha with a Th2-associated expression pattern [J].J Immunol,1998,160(3):1411-1418.
[53]SCHUTYSER E,STRUYF S,PROOST P,et al.Identification of biologically active chemokine isoforms from ascitic fluid and elevated levels of CCL18/pulmonary and activation-regulated chemokine in ovarian carcinoma [J].J Biol Chem,2002,277(27):24584-24593.
[54]LIANG WG,REN M,ZHAO F,et al.Structures of human CCL18,CCL3,and CCL4 reveal molecular determinants for quaternary structures and sensitivity to insulin-degrading enzyme [J].J Mol Biol,2015,427(6 Pt B):1345-1358.
[55]NIBBS RJ,SALCEDO TW,CAMPBELL JD,et al.C-C chemokine receptor 3 antagonism by the beta-chemokine macrophage inflammatory protein 4,a property strongly enhanced by an amino-terminal alanine-methionine swap [J].J Immunol,2000,164(3):1488-1497.
[56]KROHN SC,BONVIN P,POUDFOOT AE.CCL18 exhibits a regulatory role through inhibition of receptor and glycosaminoglycan binding [J].PLoS One,2013,8(8):e72321.
[57]LIU X,XU X,DENG W,et al.CCL18 enhances migration,invasion and EMT by binding CCR8 in bladder cancer cells [J].Mol Med Rep,2019,19(3):1678-1686.
[58]HUANG Y,MOTTA E,NANVUMA C,et al.Microglia/macrophage-derived human CCL18 promotes glioma progression via CCR8-ACP5 axis analyzed in humanized slice model [J].Cell Rep,2022,39(2):110670.
[59]DING D,ZHANG L,LIU X,et al.Chemokine CCL18 promotes phagocytosis through its receptor CCR8 rather than PITPNM3 in human microglial cells [J].J Interferon Cytokine Res,2022,42(1):19-28.
[60]JING X,PENG J,DOU Y,et al.Macrophage ERα promoted invasion of endometrial cancer cell by mTOR/KIF5B-mediated epithelial to mesenchymal transition [J].Immunol Cell Biol,2019,97(6):563-576.
[61]SCHMIDT-WOLF R,ZISSEL G.Interaction between CCL18 and GPR30 differs from the interaction between estradiol and GPR30 [J].Anticancer Res,2020,40(6):3097-3108.
[62]SHI L,ZHANG B,SUN X,et al.CC chemokine ligand 18(CCL18) promotes migration and invasion of lung cancer cells by binding to Nir1 through Nir1-ELMO1/DOC180 signaling pathway [J].Mol Carcinog,2016,55(12):2051-2062.
[63]YE H,ZHOU Q,ZHENG S,et al.Tumor-associated macrophages promote progression and the Warburg effect via CCL18/NF-kB/VCAM-1 pathway in pancreatic ductal adenocarcinoma [J].Cell Death Dis,2018,9(5):453.
[64]WANG C,LIANG H,LI Y,et al.Chemokine (C-C motif) ligand 18/membrane-associated 3/forkhead box O1 axis promotes the proliferation,migration,and invasion of intrahepatic cholangiocarcinoma [J].Bioengineered,2022,13(5):12738-12748.
[65]JIANG X,HUANG Z,SUN X,et al.CCL18-NIR1 promotes oral cancer cell growth and metastasis by activating the JAK2/STAT3 signaling pathway [J].BMC Cancer,2020,20(1):632.
[66]JIANG X,WANG J,CHEN X,et al.Elevated autocrine chemokine ligand 18 expression promotes oral cancer cell growth and invasion via Akt activation [J].Oncotarget,2016,7(13):16262-16272.
[67]CATUSSE J,WOLLNER S,LEICK M,et al.Attenuation of CXCR4 responses by CCL18 in acute lymphocytic leukemia B cells [J].J Cell Physiol,2010,225(3):792-800.
[68]LIANG WG,REN M,ZHAO F,et al.Structures of human CCL18,CCL3,and CCL4 reveal molecular determinants for quaternary structures and sensitivity to insulin-degrading enzyme [J].J Mol Biol,2015,427(6 Pt B):1345-1358.
[69]ZOHNY SF,FAYED ST.Clinical utility of circulating matrix metalloproteinase-7 (MMP-7),CC chemokine ligand 18 (CCL18) and CC chemokine ligand 11 (CCL11) as markers for diagnosis of epithelial ovarian cancer [J].Med Oncol,2010,27(4):1246-1253.
[70]MAO L,TANG Y,DENG MJ,et al.A combined biomarker panel shows improved sensitivity and specificity for detection of ovarian cancer [J].J Clin Lab Anal,2022,36(2):e24232.
[71]YUAN L,WAN J,HUANG C,et al.Evaluation of serum CCL18 as a potential biomarker for ovarian cancer [J].Cancer Biomark,2017,21(1):97-104.
[72]WANG Q,TANG Y,YU H,et al.CCL18 from tumor-cells promotes epithelial ovarian cancer metastasis via mTOR signaling pathway [J].Mol Carcinog,2016,55(11):1688-1699.
[73]LANE D,MATTE I,LAPLANTE C,et al.CCL18 from ascites promotes ovarian cancer cell migration through proline-rich tyrosine kinase 2 signaling [J].Mol Cancer,2016,15(1):58.
[74]LONG L,HU Y,LONG T,et al.Tumor-associated macrophages induced spheroid formation by CCL18-ZEB1-M-CSF feedback loop to promote transcoelomic metastasis of ovarian cancer [J].J Immunother Cancer,2021,9(12):e003973.
[75]RAJKUMAR T,SABITHA K,VIJAYALAKSHMI N,et al.Identification and validation of genes involved in cervical tumourigenesis [J].BMC Cancer,2011,11:80.
[76]ROYSE KE,ZHI D,CONNER MG,et al.Differential gene expression landscape of co-existing cervical pre-cancer lesions using RNA-seq [J].Front Oncol,2014,4:339.