|Table of Contents|

Progress in clinicopathological features and treatment of cN0 isthmus papillary thyroid carcinoma

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2023 15
Page:
2938-2943
Research Field:
Publishing date:

Info

Title:
Progress in clinicopathological features and treatment of cN0 isthmus papillary thyroid carcinoma
Author(s):
CHANG Jingtao1; LIANG Chaowei1; WANG Weiran1; JIA Baosong1; ZHANG Jin2; LIU Jing2
1.The First Clinical College of Shanxi Medical University,Shanxi Taiyuan 030001,China;2.Department of Thyroid Surgery,the First Hospital of Shanxi Medical University,Shanxi Taiyuan 030001,China.
Keywords:
isthmic thyroid carcinoma; total thyroidectomy; isthmus thyroidectomy; central lymph node dissection; ablation techniques
PACS:
R736.1
DOI:
10.3969/j.issn.1672-4992.2023.15.033
Abstract:
Papillary thyroid carcinoma（PTC),the most common pathologic type of thyroid cancer,is mostly bilateral in the glandular lobes,but a small percentage of them originate in the isthmus.Compared with adenocarcinoma,isthmic PTC presents more aggressive clinicopathological features.Due to the particularity of anatomy and biological behavior of isthmic PTC,there is a lack of clear treatment rules for clinically negative（cN0) isthmic PTC in current guidelines at home and abroad.The most commonly used treatment plan for clinicians is total thyroidectomy+preventive central region lymph node dissection（pCLND).However,under the background of advocating tumor risk stratification and personalized precision therapy,scholars have great controversies over the scope of surgical resection of PTC in the isthmus of cN0 and preventive lymph node dissection in the central region.At the same time,the continuous advancement of thermal ablation in the treatment of papillary thyroid microcarcinoma（PTMC) may also bring new ideas for the treatment of PTMC in the isthmus of cN0.In this paper,the clinicopathological features and treatment progress of PTC in cN0 isthmus were systematically reviewed to provide a reference for surgeons to choose the best treatment.

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山西省医学重点科研项目引导性科技专项（编号：2020XM57）
Last Update: 2023-06-30