|Table of Contents|

Analysis of clinical factors affecting the diagnosis of small stromal tumors in upper digestive tract by endoscopic ultrasonography

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2023 12
Page:
2260-2264
Research Field:
Publishing date:

Info

Title:
Analysis of clinical factors affecting the diagnosis of small stromal tumors in upper digestive tract by endoscopic ultrasonography
Author(s):
WANG Jia; DU Zhaozhao; LIU Huan; NIE Shan; ZHANG Mingxin; CUI Manli
Department of Gastroemterology，the First Affiliated Hospital of Xi'an Medical University，Shaanxi Xi'an 710077，China.
Keywords:
endoscopic ultrasonography; stromal tumors; subepithelial lesions
PACS:
R735
DOI:
10.3969/j.issn.1672-4992.2023.12.015
Abstract:
Objective:To evaluate the clinical factors affecting the diagnosis of small upper gastrointestinal stromal tumors(GIST) by endoscopic ultrasonography(EUS).Methods:Small upper GIST(diameter<2 cm) was diagnosed by EUS in our hospital from January 2020 to January 2022.There are 53 patients with final surgical pathology.Taking the postoperative pathology as the gold standard，the patients were divided into two groups，including EUS and postoperative pathology consistent group（30 cases) and the EUS and postoperative pathology inconsistent group（23 cases).The factors influencing the accuracy of preoperative EUS diagnosis were analyzed.Results:The mean age of subepithelial lesions(SEL) in upper digestive tract was （57.5±11.1) years old.There were no significant differences in gender，age and lesion location between the two groups（P＜0.05).The diameter of EUS lesions［（7.97±2.47）mm］ was smaller in the pathological inconsistence group than in the consistent group［（12.49±5.43）mm］.There was no statistical difference between the two groups in irregular boundary，uneven echo and lobulation.But there were significant differences in lesion origin，diameter，hyperechoic foci，cystic lesions，and surface pitting/ulceration between the two groups.Receiver operating characteristic curve(ROC) was used to analyze the characteristics of EUS，and the results indicated that lesion size had high specificity and poor sensitivity for diagnosis（SE=60.0%，SP=91.3%，AUC 0.770).The high echoic foci had good sensitivity and specificity（SE=76.7%，SP=78.3%，AUC 0.775)，and cystic structures had good sensitivity and poor specificity（SE=100.0%，SP=52.2%，AUC 0.761).Conclusion:EUS diagnosis of small GIST in the upper digestive tract may be evaluated by the size of lesions，high-echo focal points and cystic structure，but these characteristics are not unique to GIST.The origin，uneven echo and lobulation may affect the judgment of EUS.The diagnosis of small upper GIST still needs to be made in combination with other examination methods or follow-up.

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陕西省教育厅专项科研计划项目（编号：22JK0548）
Last Update: 1900-01-01