|Table of Contents|

Non-myeloablative allogeneic hematopoietic stem cell transplantation for the treatment of 2 patients with hematological malignancies with long term survival and natural birth

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2023 11
Page:
2102-2104
Research Field:
Publishing date:

Info

Title:
Non-myeloablative allogeneic hematopoietic stem cell transplantation for the treatment of 2 patients with hematological malignancies with long term survival and natural birth
Author(s):
LIU Juan; LYU Panpan; HUANG Xiaomei; QU Yuanyuan; YANG Yakun; SUN Wanjun
Department of Hematology,Chinese PLA Rocket Force Characteristic Medical Center,Beijing 100088,China.
Keywords:
allogeneic hematopoietic stem cell transplantation; non myeloablative regimen; long term survival; fertility
PACS:
R733.3
DOI:
10.3969/j.issn.1672-4992.2023.11.023
Abstract:
Objective：To explore the efficacy and fertility of non-myeloablative(NMA) allogeneic hematopoietic stem cell transplantation(allo-HSCT) for hematologic malignancies.Methods:The process and fertility of 2 patients with hematologic malignancies treated with NMA allo-HSCT were reported,and the related literatures were reviewed.Results：One 25-year-old female patient with acute myeloid leukemia(AML) transformed from myelodysplastic syndrome(MDS) and one 32-year-old female patient with non Hodgkin's lymphoma(NHL) received NMA allo-HSCT treatment.Up to the follow-up date(2022-10-01),2 patients had diseases free survival with 190 months and 115 months,respectively,and both had naturally given birth to healthy children.Conclusion:NMA allo-HSCT benefited hematologic malignancies with long-term survival and preserved fertility.

References:

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Memo

Memo:
首都卫生发展科研专项自主创新基金（编号：2022-2-5111）
Last Update: 2023-04-28