|Table of Contents|

Research progress on gene mutation characteristics of ovarian clear cell carcinoma and related targeting and immunotherapy

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2023 09
Page:
1756-1760
Research Field:
Publishing date:

Info

Title:
Research progress on gene mutation characteristics of ovarian clear cell carcinoma and related targeting and immunotherapy
Author(s):
MA JinglanYIN Xia
Department of Obstetrics and Gynecology,Renji Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai Key Laboratory of Gynecologic Oncology,Shanghai 200127,China.
Keywords:
ovarian clear cell carcinomagene mutationtargeted therapyimmunotherapy
PACS:
R737.31
DOI:
10.3969/j.issn.1672-4992.2023.09.033
Abstract:
Ovarian clear cell carcinoma(OCCC) is a distinct histological subtype of epithelial ovarian cancer(EOC) with poor prognosis due to the primary platinum chemo-resistance.Investigation of its unique molecular characteristics is crucial to figure out effective therapeutic targets,which is important in improving clinical efficacy and prognosis for patients.We comprehensively reviews the recent progress of treatment related mutation characteristics including ARID1,PI3K/AKT/mTOR,APOBEC.

References:

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Memo

Memo:
National Natural Science Foundation of China(No.82173077);国家自然科学基金面上项目(编号:82173077);北京康华中西医发展基金会医学科研项目(编号:KH-2021-LLZX-018);上海申康医院发展中心临床创新研发项目(编号:SHDC2020CR3057B);上海交通大学医工交叉项目(编号:YG2021GD02)
Last Update: 2023-03-30