|Table of Contents|

Analysis of the survival trend of ovary cancer in Qidong City，Jiangsu Province from 1977 to 2016

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2023 09
Page:
1731-1735
Research Field:
Publishing date:

Info

Title:
Analysis of the survival trend of ovary cancer in Qidong City，Jiangsu Province from 1977 to 2016
Author(s):
ZHU Jian; XU Yuanyou; ZHANG Yonghui; WANG Jun; CHEN Yongsheng; DING Lulu; CHEN Jianguo; HUANG Qinjie
The Affiliated Qidong Hospital of Nantong University，Qidong People's Hospital，Qidong Liver Cancer Institute，Jiangsu Qidong 226200，China.
Keywords:
ovary cancer; survival; trends; Qidong
PACS:
R737.31
DOI:
10.3969/j.issn.1672-4992.2023.09.028
Abstract:
Objective:To analyze the survival rate of ovary cancer cases in the whole population of Qidong City，Jiangsu Province in the past 40 years，to provide a basis for prognosis evaluation and prevention.Methods:Based on the cancer registration case data in Qidong City，the observed survival rate(OS) and relative survival rate(RS) was calculated using the Hakulinen method in SURV3.01 software，and statistical test was performed using Hakulinen's likelihood ratio test.Age-standardized relative survival rate was calculated using International Cancer Survival Standard(ICSS).Joinpoint regression analysis was performed with Joinpoint 4.7.0.0 software to calculate the annual percentage change(APC) of ovary cancer survival.Results:1-RS increased from 31.02% in 1977－1981 to 78.81% in 2012－2016，3-RS increased from 18.50% in 1977－1981 to 57.91% in 2012－2016，5-RS increased from 19.47% in 1977－1981 to 49.54% in 2012－2016.The upward trend of RS was statistically significant(χ2=56.09，P＜0.001).Age-standardized 1-RS increased from 35.35% in 1977－1981 to 65.96% in 2012－2016.Age-standardized 3-RS increased from 20.59% in 1977－1981 to 45.27% in 2012－2016.Age-standardized 5-RS increased from 24.61% in 1977－1981 to 38.66% in 2012－2016.The 5-RS for the age groups of 15~24，25~34，35~44，45~54，55~64，65~74，and over 75 years old were 47.71%，43.03%，52.66%，49.35%，33.77%，34.48% and 24.24%，respectively.There was statistically significant difference among different age groups(χ2=61.00，P＜0.001).The overall APC of 1-OS，3-OS，5-OS from 1977 to 2016 was 1.57%(t=4.189，P=0.006)，2.19%(t=6.142，P=0.001)，1.63%(t=3.170，P=0.019)，and the overall APC of 1-RS，3-RS，5-RS from 1977 to 2016 was 1.57%(t=4.230，P=0.005)，2.18%(t=6.389，P=0.001)，1.61%(t=3.304，P=0.016)，and the overall APC of age-standardized 1-RS，3-RS，5-RS from 1977 to 2016 was 1.52%(t=6.770，P=0.001)，1.99%(t=4.761，P=0.003)，1.31%(t=2.481，P=0.048)，with statistically significant upward trend.Conclusion:The survival rate of ovary cancer in Qidong has been improved to a certain extent in the past 40 years recent years，but there is still a proportion for improvement.We should continue to pay attention to the diagnosis and treatment of ovary cancer.

References:

［1］SUNG H，FERLAY J，SIEGEL RL，et al.Global cancer statistics 2020:GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries［J］.CA Cancer J Clin，2021，71(3):209-249.
［2］ZHENG RS，ZHANG SW，ZENG HM，et al.Cancer incidence and mortality in China，2016［J］.JNCC，2022，2(1)：1-9.
［3］朱健，蒋明博，武鸣，等.江苏省2006-2015年卵巢癌变化趋势及现状分析［J］.中华流行病学杂志，2020，41(11):1859-1864. ZHU J，JIANG MB，WU M，et al.Analysis on incidence and mortality of ovarian cancer in Jiangsu Province，2006-2015［J］.Chinese Journal of Epidemiology，2020，41(11):1859-1864.
［4］朱健，陈永胜，张永辉，等.江苏省启东市肺癌45年死亡趋势分析［J］.中华预防医学杂志，2020，54(12):1457-1460. ZHU J，CHEN YS，ZHANG YH，et al.An analysis of mortality trends for lung cancer during 1972-2016 in Qidong City of Jiangsu Province［J］.Chinese Journal of Preventive Medicine，2020，54(12):1457-1460.
［5］国家癌症中心.中国肿瘤登记工作指导手册(2016)［M］.北京:人民卫生出版社，2016:152-156. National Central Cancer Registry.Guideline of Chinese cancer registration(2016)［M］.Beijing:People's Medical Press，2016:152-156.
［6］BRAY F，COLOMBET M，MERY M，et al.Cancer incidence in five continents，Vol XI［M］.Lyon：IARC，2021：550-551.
［7］赫捷.2018中国肿瘤登记年报［M］.北京:人民卫生出版社，2019:336. HE J.China cancer registry annual report 2018［M］.Beijing：People's Medical Publishing House，2019:336.
［8］蒋宇飞，李卓颖，袁蕙芸，等.全人群肿瘤登记资料生存率分析方法的研究进展［J］.中国肿瘤，2021，30(10):777-783. JIANG YF，LI ZY，YUAN HY，et al.Progress on the statistical methods and application of survival analysis for the population-based cancer registration［J］.China Cancer，2021，30(10):777-783.
［9］Finnish Cancer Registry.SURV3：Windows software for relative survival analysis［EB/OL］.(2010-09-01)［2022-03-01］.http://www.cancerregistry.fi/surv3/ 2010-09-01.
［10］CORAZZIARI I，QUINN M，CAPOCACCIA R.Standard cancer patient population for age standardising survival ratios［J］.Eur J Cancer，2004，40(15):2307-2316.
［11］李辉章，杜灵彬.Joinpoint回归模型在肿瘤流行病学时间趋势分析中的应用［J］.中华预防医学杂志，2020，54(8):908-912. LI HZ，DU LB.Application of Joinpoint regression model in cancer epidemiological time trend analysis［J］.Chinese Journal of Preventive Medicine，2020，54(8):908-912.
［12］ALLEMANI C，MATSUDA T，DI CARLO V，et al.Global surveillance of trends in cancer survival 2000-14(CONCORD-3)：analysis of individual records for 37 513 025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries［J］.Lancet，2018，391(10125):1023-1075.
［13］ZENG H，CHEN W，ZHENG R，et al.Changing cancer survival in China during 2003-15：a pooled analysis of 17 population-based cancer registries［J］.Lancet Glob Health，2018,6(5):e555-e567.
［14］魏矿荣，梁智恒，李柱明.2003-2013年广东省中山市主要癌症净生存率分析［J］.中国肿瘤，2020，29(2):103-107. WEI KR，LIANG ZH，LI ZM.Net survival of major cancers in Zhongshan City of Guangdong Province from 2003 to 2013［J］.China Cancer，2020，29(2):103-107.
［15］龚巍巍，罗胜兰，胡如英，等.2005-2010年浙江省女性乳腺癌、宫颈癌与卵巢癌生存率分析［J］.中华预防医学杂志，2014，48(5):366-369. GONG WW，LUO SL，HU RY，et al.Analysis of survival rate of breast，cervical，and ovarian cancer patients during 2005-2010 in Zhejiang Province，China［J］.Chinese Journal of Preventive Medicine，2014，48(5):366-369.
［16］ARNOLD M，RUTHERFORD MJ，BARDOT A，et al.Progress in cancer survival，mortality，and incidence in seven high-income countries 1995-2014(ICBP SURVMARK-2)：a population-based study［J］.Lancet Oncol，2019,20(11):1493-1505.
［17］陶佳宁，艾玲娜.卵巢癌高危因素的主要影响及早期诊断治疗的效果分析［J］.实用妇科内分泌电子杂志，2019，6(12):96. TAO JN，AI LN.Analysis of the main impact of high risk factors in ovarian cancer and analysis of early diagnosis［J］.Journal of Practical Gynecologic Endocrinology，2019，6(12):96.
［18］杨玲，周建政.人附睾蛋白4在上皮性卵巢癌中的应用价值［J］.临床与病理杂志，2021，41(3):683-688. YANG L，ZHOU JZ.Application value of human epididymis protein 4 in epithelial ovarian cancer［J］.International Journal of Pathology and Clinical Medicine，2021，41(3):683-688.
［19］AMIT A，HODES A，LAVIE O，et al.The role of 18F-FDG PET/CT in predicting secondary optimal de-bulking in patients with recurrent ovarian cancer［J］.Surg Oncol，2017，26(4):347-351.
［20］赖祝琴，吴宏，杨振宇，等.超声造影联合肿瘤标志物筛查早期卵巢癌的研究［J］.泰山医学院学报，2016，37(6):620-622. LAI ZQ，WU H，YANG ZY，et al.Screening of early stage ovarian cancer by contrast enhanced ultrasound with tumor marker［J］.Journal of Taishan Medical College，2016，37(6):620-622.
［21］辜卫红，胡天惠，薛涛.血清CA125、HE4联合阴道彩色多普勒在卵巢癌高危人群早期筛查中的临床价值［J］.重庆医学，2017，47(12):35-37. GU WH，HU TH，XUE T.Clinical value of serum CA125 and HE4 combined with vaginal color Doppler in early screening of ovarian cancer among high-risk populations［J］.Chongqing Medicine，2017，47(12):35-37.
［22］张静云，袁婷，李玉娟，等.长链非编码RNA LincROR在卵巢癌筛查中的应用［J］.临床检验杂志，2019，37(8):608-611. ZHANG JY，YUAN T，LI YJ，et al.Application of long non-coding RNA LincROR in the screening of ovarian cancer［J］.Chinese Journal of Clinical Laboratory Science，2019，37(8):608-611.
［23］丁璐璐，朱健，张永辉，等.1972-2016年江苏省启东市女性生殖系统主要恶性肿瘤死亡趋势分析［J］.中国肿瘤，2021，30(4):274-279. DING LL，ZHU J，ZHANG YH，et al.Mortality trend of female reproductive system cancer from 1972 to 2016 in Qidong City,Jiangsu Province［J］.China Cancer，2021，30(4):274-279.
［24］严永锋，王军，徐源佑，等.1987-2016年江苏省启东市前列腺癌生存率分析［J］.中国肿瘤，2022，31(6):457-462. YAN YF，WANG J，XU YY，et al.Survival trend of prostate cancer in Qidong County，Jiangsu Province from 1987 to 2016［J］.China Cancer，2022，31(6):457-462.

Memo

Memo:
江苏省南通市基础科学研究和社会民生科技计划项目（编号：JCZ2022050）
Last Update: 2023-03-30