|Table of Contents|

Clinical efficacy of total laparoscopic distal gastrectomy in treatment for elderly gastric cancer patients

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2023 09
Page:
1671-1677
Research Field:
Publishing date:

Info

Title:
Clinical efficacy of total laparoscopic distal gastrectomy in treatment for elderly gastric cancer patients
Author(s):
SU Zhong; MENG Weishan
Department of General Surgery,the First Hospital of Qinhuangdao,Hebei Qinhuangdao 066000,China.
Keywords:
gastric cancer; elderly; total laparoscopic digestive tract reconstruction; short-term outcomes; immune function
PACS:
R735.2
DOI:
10.3969/j.issn.1672-4992.2023.09.016
Abstract:
Objective：To investigate the clinical efficacy of total laparoscopic distal gastrectomy (DG) in the treatment of elderly gastric cancer (GC) patients.Methods:Elderly GC patients (aged over 70 years) who received laparoscopic distal gastrectomy in our hospital between January 2019 and December 2021 were included.After propensity score-matching,patients were classified into the observation group with total laparoscopic distal gastrectomy (n=40) and the control group with laparoscopic assisted distal gastrectomy(n=80) according to the surgical approaches.The short-term outcomes,postoperative complications,changes in immune function,quality of life (QOL),and survival were compared between the groups.Results:Compared with the control group,patients in the observation group had comparable postoperative morbidity (10% vs 23%,P=0.095),but had significantly shorter time to ambulation,time to first flatus,and postoperative hospital stay (P＜0.05).Moreover,the levels of white blood cells and C-reactive protein were significantly lower and the levels of CD3+,CD4+,and CD4+/CD8+ were significantly higher in the observation group than in the control group.In terms of the QOL,the scores of pain and constipation were significantly better in the observation group than in the control group (P＜0.05).No local recurrence was observed during the follow-up.Conclusion:Compared with the traditional laparoscopic assisted DG,total laparoscopic DG had faster recovery,less impact on the immune function,lower complications,and higher QOL in treating elderly GC patients,which should be further applied in the clinical practice.

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Last Update: 2023-03-30