|Table of Contents|

Correlation analysis of blood lipids with phase angle and percent body fat in tumor patients

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2023 08
Page:
1536-1541
Research Field:
Publishing date:

Info

Title:
Correlation analysis of blood lipids with phase angle and percent body fat in tumor patients
Author(s):
YU Jiawen1; 2; YAO Wenjuan1; 2; JIANG Hao1; CHEN Lihao1; 2; WANG Hui1; ZHU Heling1; 2
1.Department of Oncology;2.Department of Clinical Nutrition,Anqing First People's Hospital of Anhui Medical University/Anqing First People's Hospital of Anhui Province,Anhui Anqing 246052,China.
Keywords:
nutritional status; tumor; blood lipid; percentage of body fat; phase angle
PACS:
R730.6
DOI:
10.3969/j.issn.1672-4992.2023.08.027
Abstract:
Objective:To investigate the influencing factors of blood lipids and the correlation of blood lipids with phase angle (PA) and percent body fat (PBF) in tumor patients,and to provide reference for nutritional management and research direction of tumor patients.Methods：From December 2020 to April 2022,totally 159 tumor patients admitted to our hospital were selected.Clinical data,patient generated subjective global assessment (PG-SGA) score,medication history,past medical history,personal history,results of blood lipid examination and body composition analysis were collected.The differences of blood lipids and PBF in patients with different clinical features were compared and the correlation of blood lipid level and PG-SGA with PA as well as PBF were analyzed.Results：Triglyceride (TG) and PBF of different tumor patients were significantly different (P＜0.05).The total cholesterol (TC) and TG of female,young and low performance status (PS) score patients were higher than those of male,old and high PS score patients (P＜0.05).Compared with non-smoking patients,smokers had lower TG and apolipoprotein A (Apo-A) (P＜0.05).What's more,patients with long-term alcohol consumption had lower high density lipoprotein (HDL) than non-drinking patients (P＜0.05).The levels of TC and low density lipoprotein (LDL) in patients with moderate malnutrition were the lowest (P＜0.05).TG decreased monotonously with the deterioration of nutritional status.There was no difference in blood lipid levels among different risk groups after grouping antitumor treatment measures according to the risk of dyslipidemia.PA was negatively correlated with PG-SGA (r=-0.425,P＜0.001),whereas it was positively correlated with TC,TG and LDL (P＜0.05).PBF was positively correlated with TC,TG and LDL (P＜0.001).Notably,after excluding the influence of gender,the results of partial correlation analysis demonstrated that PBF was still positively correlated with TC,TG and LDL (P＜0.05).Conclusion：The blood lipid of tumor patients is affected by many factors.TC,TG and LDL are positively correlated with PA and PBF in tumor patients.Tumor patients should prevent hypolipidemia.The effects of lipid metabolism regulation therapy and antitumor drugs on dyslipidemia should be further studied.

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安幑医科大学校基金资助项目（编号：2022xkj230）
Last Update: 1900-01-01