|Table of Contents|

The features and clinical significance of deep submucosa invasion for early colorectal cancer with JNET 2B type

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2023 08
Page:
1471-1475
Research Field:
Publishing date:

Info

Title:
The features and clinical significance of deep submucosa invasion for early colorectal cancer with JNET 2B type
Author(s):
WANG Jia; DU Zhaozhao; LIU Huan; NIE Shan; ZHANG Mingxin
Department of Gastroemterology,the First Affiliated Hospital of Xi'an Medical University,Shaanxi Xi'an 710077,China.
Keywords:
Japan NBI Expert Team classification; early colorectal cancer; deep invasion
PACS:
R735.3
DOI:
10.3969/j.issn.1672-4992.2023.08.015
Abstract:
Objective:To investigate the diagnostic efficacy of invasion depth in early colorectal cancer with JNET 2B type based on endoscopic features.Methods:A total of 47 early colorectal cancers with JNET 2B type diagnosed in our hospital were enrolled in this study.Endoscopic features of each lesion included loss of lobulation,excavation,demarcated depressed area,fullness,fold convergency,invasive pit patterns or invasive vascular patterns or JNET 2B-high.The association between endoscopic features and invasion depth was analyzed.Results:The loss of lobulation had a higher frequency of SM-d invasion compared with M/SM-s invasion(64.7% vs 13.3%,P<0.001).The fullness also had a higher frequency of SM-d invasion compared with M/SM-s invasion(64.7% vs 6.7%,P<0.001).Similar results were founding for lesions with invasive pit patterns or invasive vascular patterns or JNET 2B-high(76.5% vs 10.0%,P<0.001;94.1% vs 10.0%,P<0.001,respectively).No statistical difference was found for lesions with features of excavation,demarcated depressed area,or fold convergency.Conclusion:JNET 2B type colorectal lesions with features of loss of lobulation,fullness,invasive pit patterns or invasive vascular patterns or JNET 2B-high have a higher frequency of SM-d invasion,and surgical intervention is recommended.Surgical intervention would be recommended for lesions with these features.

References:

［1］SEUNG WOOK HONG,JEONG-SIK BYEON.Endoscopic diagnosis and treatment of early colorectal cancer［J］.Intest Res,2022，20(3):281-290.
［2］TANAKA S,KASHIDA H,SAITO Y,et al.Japan gastroenterological endoscopy society guidelines for colorectal endoscopic submucosal dissection/endoscopic mucosal resection ［J］.Dig Endosc,2020，32(2):219-239.
［3］柏愚,杨帆,马丹,等.中国早期结直肠癌筛查及内镜诊治指南(2014年,北京)［J］.中华消化内镜杂志,2015,32(06):341-360. BAI YU,YANG FAN,MA D,et al.Guidelines for screening and endoscopic diagnosis of early colorectal cancer in China (2014,Beijing) ［J］.Chinese Journal of Digestive Endoscopy,2015,32(06):341-360.
［4］TANAKA S,KASHIDA H,SAITO Y,et al.JGES guidelines for colorectal endoscopic submucosal dissection/endoscopic mucosal resection ［J］.Dig Endosc,2015,27(4):417-434.
［5］SANO Y,TANAKA S,KUDO SE,et al.Narrow-band imaging (NBI) magnifying endoscopic classification of colorectal tumors proposed by the Japan NBI Expert Team ［J］.Dig Endosc,2016,28(5):526-533.
［6］IKEHARA H,SAITO Y,MATSUDA T,et al.Diagnosis of depth of invasion for early colorectal cancer using magnifying colonoscopy ［J］.J Gastroenterol Hepatol,2010,25(5):905-912.
［7］乔伟光，陈振煜，谭文欣，等.基于蓝光成像和联动成像的结肠病变检查策略［J］.中华消化内镜杂志,2019,36(12):881-885. QIAO WG,CHEN ZY,TAN WX.Strategies for detecting colonic lesions based on BLI and LCI ［J］.Chinese Journal of Digestive Endoscopy,2019,36(12):881-885.
［8］HASHIGUCHI Y,MURO K,SAITO Y,et al;Japanese society for cancer of the colon and rectum.Japanese society for cancer of the colon and rectum (JSCCR) guidelines 2019 for the treatment of colorectal cancer ［J］.Int J Clin Oncol,2020,25(1):1-42.
［9］BO-IN LEE,TAKAHISA MATSUDA.Estimation of invasion depth:the first key to successful colorectal ESD［J］.Clin Endosc,2019,52(2):100-106.
［10］YOSHIDA N,YAGI N,INADA Y,et al.Ability of a novel blue laser imaging system for the diagnosis of colorectal polyps ［J］.Dig Endosc,2014,26(2):250-258.
［11］谭文欣,黄颖,彭阳,等.蓝光成像结合佐野分型对结直肠侧向发育型肿物的诊断价值［J］.现代消化及介入诊疗,2020，25(5):581-584. TAN WX,HUANG Y,PENG Y,et al.Diagnostic value of blue light imaging combined with Sano typing in colorectal lateral developmental tumors ［J］.Modern Digestion & Intervention,2020,25(5):581-584.
［12］彭群,黄颖,彭阳,等.蓝光成像结合NICE分型对结直肠侧向发育型肿物的诊断价值［J］.现代消化及介入诊疗,2020,25(5):572-575,580. PENG Q,HUANG Y,PENG Y,et al.Diagnostic value of blue light imaging combined with NICE typing in colorectal lateral developmental tumors ［J］.Modern Digestion & Intervention,2020,25(5):572-575,580.
［13］HUANG SL,TAN WX,PENG Q,et al.Blue laser imaging combined with JNET (Japan NBI Expert Team) classification for pathological prediction of colorectal laterally spreading tumors ［J］.Surg Endosc,2021,35(10):5430-5440.
［14］KOBAYASHI S,YAMADA M,TAKAMARU H,et al.Diagnostic yield of the Japan NBI expert team (JNET) classification for endoscopic diagnosis of superficial colorectal neoplasms in a large-scale clinical practice database［J］.United European Gastroenterology Journal,2019,7(7):914-923.
［15］ITO R,IKEMATSU H,MURANO T,et al.Diagnostic ability of Japan narrow-band imaging expert team classification for colorectal lesions by magnifying endoscopy with blue laser imaging versus narrow-band imaging［J］.Endoscopy International Open,2021,9(2):E271-E277.

Memo

Memo:
陕西省教育厅专项科研计划项目（编号：22JK0548）
Last Update: 1900-01-01