[1] LEHAR SM,NACHT M,JACKS T,et al.Identification and cloning of EI24,a gene induced by p53 in etoposide-treated cells［J］.Oncogene,1996,12(6):1181-1187.
[2] GU Z,GILBERT DJ,VALENTINE VA,et al.The p53-inducible gene EI24/PIG8 localizes to human chromosome 11q23 and the proximal region of mouse chromosome 9［J］.Cytogenet Cell Genet,2000,89(3-4):230-233.
[3] ZHAO X,AYER RE,DAVIS SL,et al.Apoptosis factor EI24/PIG8 is a novel endoplasmic reticulum-localized Bcl-2-binding protein which is associated with suppression of breast cancer invasiveness［J］.Cancer Res,2005,65(6):2125-2129.
[4] YUAN L,LIU Q,WANG Z,et al.EI24 tethers endoplasmic reticulum and mitochondria to regulate autophagy flux［J］.Cellular and Molecular Life Sciences,2020,77(8):1591-1606.
[5] GU Z,FLEMINGTON C,CHITTENDEN T,et al.ei24,a p53 response gene involved in growth suppression and apoptosis［J］.Molecular and Cellular Biology,2000,20(1):233-241.
[6] ZHENG P,CHEN Q,TIAN X,et al.DNA damage triggers tubular endoplasmic reticulum extension to promote apoptosis by facilitating ER-mitochondria signaling［J］.Cell Res,2018,28(8):833-854.
[7] YUAN L,WANG H,LIU Q,et al.Etoposide-induced protein 2.4 functions as a regulator of the calcium ATPase and protects pancreatic β-cell survival［J］.Journal of Biological Chemistry,2018,293(26):10128-10140.
[8] XU Y,CHEN J,CHEN J,et al.EI24 promotes cell adaption to ER stress by coordinating IRE1 signaling and calcium homeostasis［J］.EMBO Reports,2022,23(3):e51679.
[9] LEVINE B,KROEMER G.Autophagy in the pathogenesis of disease［J］.Cell,2008,132(1):27-42.
[10] ZHENG Q,CHEN Y,CHEN D,et al.Calcium transients on the ER surface trigger liquid-liquid phase separation of FIP200 to specify autophagosome initiation sites［J］.Cell,2022,185(22):4082-4098.
[11] PENG S.Calcium transients at ER subdomains initiate autophagosome formation:a single spark can start a prairie fire［J］.Function (Oxf),2023,4(2):d4.
[12] TIAN Y,LI Z,HU W,et al.C.elegans screen identifies autophagy genes specific to multicellular organisms［J］.Cell,2010,141(6):1042-1055.
[13] ZHAO YG,ZHAO H,MIAO L,et al.The p53-induced gene Ei24 is an essential component of the basal autophagy pathway［J］.Journal of Biological Chemistry,2012,287(50):42053-42063.
[14] ZHANG X,MAO Y,PENG W,et al.Autophagy-related protein EI24 delays the development of pulmonary fibrosis by promoting autophagy［J］.Life Sciences,2021,264:118664.
[15] CHOI J,DEVKOTA S,SUNG YH,et al.EI24 regulates epithelial-to-mesenchymal transition and tumor progression by suppressing TRAF2-mediated NF-κB activity［J］.Oncotarget,2013,4(12):2383-2396.
[16] MAO Y,ZHANG X,PENG W,et al.EI24 alleviates renal interstitial fibrosis through inhibition of epithelial-mesenchymal transition and fibroblast activation［J］.The FASEB Journal,2021,35(1):e21239.
[17] DUAN L,MA J,YANG W,et al.EI24 inhibits cell proliferation and drug resistance of esophageal squamous cell carcinoma［J］.Frontiers in Oncology,2020,10:1570.
[18] LI F,GUO D,ZHI S,et al.Etoposide-induced protein 2.4 ameliorates high glucose-induced epithelial-mesenchymal transition by activating adenosine monophosphate-activated protein kinase pathway in renal tubular cells［J］.Int J Biochem Cell Biol,2022,142:106117.
[19] MORK CN,FALLER DV,SPANJAARD RA.Loss of putative tumor suppressor EI24/PIG8 confers resistance to etoposide［J］.FEBS Letters,2007,581(28):5440-5444.
[20] CHOI J,JANG J,CHOI Y,et al.Reduced expression of EI24 confers resistance to gefitinib through IGF-1R signaling in PC9 NSCLC cells［J］.Lung Cancer,2015,90(2):175-181.
[21] LIEU KG,SHIM E,WANG J,et al.The p53-induced factor Ei24 inhibits nuclear import through an importin β-binding-like domain［J］.Journal of Cell Biology,2014,205(3):301-312.
[22] ZANG Y,ZHU L,LI T,et al.EI24 suppresses tumorigenesis in pancreatic cancer via regulating c-Myc［J］.Gastroenterology Research and Practice,2018,2018:1-12.
[23] HWANG M,JUN DW,KANG EH,et al.EI24,as a component of autophagy,is involved in pancreatic cell proliferation［J］.Frontiers in Oncology,2019,9:652.
[24] 张勤，黄安中，沈冯佳，等.含有WW结构域的泛素蛋白连接酶1降解依托泊苷诱导蛋白24并促进肝癌细胞增殖［J］.中华肿瘤杂志,2020,42(3):203-209.
ZHANG Q,HUANG AZ,SHEN FJ,et al.WWP1 promotes cell proliferation in hepatocellular carcinoma through ubiquitin-degradation EI24［J］.Chin J Oncol,2020,42(3):203-209.
[25] ZHOU W,YANG W,YANG J,et al.miR-483 promotes the development of colorectal cancer by inhibiting the expression level of EI24［J］.Mol Med Rep,2021,24(2):567.
[26] NAM TW,PARK SY,LEE JH,et al.Effect of EI24 expression on the tumorigenesis of Apc colorectal cancer mouse model［J］.Biochemical and Biophysical Research Communications,2019,514(4):1087-1092.
[27] DEVKOTA S,SUNG YH,CHOI J,et al.Ei24-deficiency attenuates protein kinase Cα signaling and skin carcinogenesis in mice［J］.The International Journal of Biochemistry & Cell Biology,2012,44(11):1887-1896.
[28] LI J,ZHAO B,CHEN S,et al.Downhill running induced DNA damage enhances mitochondrial membrane permeability by facilitating ER-mitochondria signaling［J］.Journal of Muscle Research and Cell Motility,2022,43(4):185-193.
[29] NAM T,HAN JH,DEVKOTA S,et al.Emerging paradigm of crosstalk between autophagy and the ubiquitin-proteasome system［J］.Mol Cells,2017,40(12):897-905.
[30] SUNG YH,JIN Y,KANG Y,et al.Ei24,a novel E2F target gene,affects p53-independent cell death upon ultraviolet C irradiation［J］.Journal of Biological Chemistry,2013,288(43):31261-31267.
[31] YANG W,ZHOU W,ZHAO X,et al.Prognostic role and immune infiltration characteristics of EI24 in multiple cancer types［J］.Expert Review of Molecular Diagnostics,2023,23(5):457-469.
[32] DEVKOTA S,JEONG H,KIM Y,et al.Functional characterization of EI24-induced autophagy in the degradation of RING-domain E3 ligases［J］.Autophagy,2016,12(11):2038-2053.