|Table of Contents|

The application effect of three-dimensional visualization technology,fluorescence imaging system combined with ultrasonography for surgery of small hepatocellular carcinoma associated with severe liver cirrhosis

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2024 06
Page:
1089-1093
Research Field:
Publishing date:

Info

Title:
The application effect of three-dimensional visualization technology,fluorescence imaging system combined with ultrasonography for surgery of small hepatocellular carcinoma associated with severe liver cirrhosis
Author(s):
HE XiaojunBAI LiangliangDU Xilin
Department of General Surgery,the Second Affiliated Hospital of Air Force Medical University,Shaanxi Xi'an 710038,China.
Keywords:
primary liver cancercirrhosisthree-dimensional visualizationindocyanine green (ICG)fluorescence imaging
PACS:
R735.1
DOI:
10.3969/j.issn.1672-4992.2024.06.018
Abstract:
Objective:To summarize the experience of surgery of small hepatocellular carcinoma associated with severe liver cirrhosis by using combination of three-dimensional visualization technology,indocyanine green fluorescence imaging system and ultrasonography.Methods:The data of 63 patients with small hepatocellular carcinoma who underwent laparotomy and laparoscopic surgery for severe liver cirrhosis at the General Surgery Department of our hospital from January 2019 to December 2022 were retrospectively analyzed.On the basis of intraoperative ultrasound assistance,the patients were divided into an observation group (n=33) and a control group (n=30) according to whether three-dimensional visualization and fluorescence imaging technology were combined.The surgical treatment,laboratory test indicators and postoperative complications of the two groups of patients were compared.Results:The operation time of the observation group was significantly shorter than that of the control group,and the intraoperative blood loss was also significantly less than that of the control group.The residual lesions after operation were also less than those in the control group.There were statistically significant differences in ALT,AST and TBil between the two groups 3 days after operation (P£¼0.05),and the levels of ALT,AST and TBil in the observation group were significantly lower than those in the control group.Conclusion:For small hepatocellular carcinoma patients with severe cirrhosis,the combination of three-dimensional visualization technology,indocyanine green fluorescence imaging technology,and ultrasound technology during open or laparoscopic surgery can help locate hepatocellular carcinoma and improve the treatment effect.

References:

£Û1£Ý »ÆÖ¾Ó£¬ÕŶþÀ×,³ÂТƽ.¸ÎÓ²»¯³Ì¶È·Ö¼¶Óë¸Î°©Íâ¿ÆÖÎÁƾö²ß£ºÍ¬¼Ã¾­Ñé£ÛJ£Ý.ÖлªÍâ¿ÆÔÓÖ¾,2019£¬57(6)£º408-411. HUANG ZY,ZHANG EL,CHEN XP.Staging the severity of liver cirrhosis and decision of surgical treatment for hepatocellular carcinoma:Tongji experience£ÛJ£Ý.Chin J Surg,2019,57(6):408-411.
£Û2£Ý ¹ú¼ÒÎÀÉú½¡¿µÎ¯°ì¹«Ìü.Ô­·¢ÐԸΰ©ÕïÁÆÖ¸ÄÏ(2022Äê°æ) £ÛJ£Ý.ÁÙ´²¸Îµ¨²¡ÔÓÖ¾,2022,38(02):288-303. General Office of National Health Commission.Standard for diagnosis and treatment of primary liver cancer (2022 edition) £ÛJ£Ý.J Clin Hepatol,2022,38(02):288-303.
£Û3£Ý PARK JW,CHEN M,COLOMBO M,et al.Global patterns of hepatocellular carcinoma management from diagnosis to death:the BRIDGE study£ÛJ£Ý.Liver Int,2015,35(9):2155-2166.
£Û4£Ý YE F,LIU J,OUYANG H.Gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging and multidetector-row computed tomography for the diagnosis of hepatocellular carcinoma:a systematic review and meta-analysis£ÛJ£Ý.Medicine (Baltimore),2015,94(32):e1157.
£Û5£Ý KOKUDO N,TAKEMURA N,ITO K,et al.The history of liver surgery:achievements over the past 50 years£ÛJ£Ý.Ann Gastroenterol Surg,2020,4(2):109-117.
£Û6£Ý LAMAD¦I W,GLOMBITZA G,FISCHER L,et al.The impact of 3-dimensional reconstructions on operation planning in liver surgery£ÛJ£Ý.Arch Surg,2000,135(11):1256-1261.
£Û7£Ý ÂÞÏæ,ÀîÌÎ,Öì¼ÌÒµ,µÈ.ÈýάÖؽ¨ÔÚ¾«×¼¸ÎÇгýÖÎÁƸ´ÔÓÔ­·¢ÐԸΰ©ÊõÇ°ÆÀ¹ÀÖеÄÓ¦ÓãÛJ£Ý.ÖлªÒ½Ñ§ÔÓÖ¾,2021,101(28)£º2210-2215. LUO X,LI T,ZHU JY,et al.Application value of three-dimensional reconstruction in preoperative evaluation of precise hepatectomy for complex primary liver cancer£ÛJ£Ý.Chin Med J,2021,101(28)£º2210-2215.
£Û8£Ý ÕÅçâç÷,·½³Û»ª.Ô­·¢ÐԸΰ©Èýά¿ÉÊÓ»¯¾«×¼ÕïÁÆÓë¶þά³ÉÏñ¼¼ÊõÁÆЧ±È½ÏMeta·ÖÎö£ÛJ£Ý.ÖйúʵÓÃÍâ¿ÆÔÓÖ¾,2019,39(08):854-860. ZHANG WQ,FANG CH.Three-dimensional visualization technology for precise diagnosis and treatment of primary liver cancer:a meta-analysis£ÛJ£Ý.Chin J Pract Surg,2019,39(08):854-860.
£Û9£Ý ISHIZAWA T,FUKUSHIMA N,SHIBAHARA J,et al.Real-time identification of liver cancers by using indocyanine green fluorescent imaging£ÛJ£Ý.Cancer,2009,115(11):2491-2504.
£Û10£Ý XU C,CUI X,JIA Z,et al.A meta-analysis of short-term and long-term effects of indocyanine green fluorescence imaging in hepatectomy for liver cancer£ÛJ£Ý.Photodiagnosis Photodyn Ther,2023,42:103497.
£Û11£Ý IANCU I,BARTOÿðþ‰C A,CIOLTEAN C,et al.Up to date and perspectives for hepatocellular carcinoma£Ü's intraoperative ultrasound£ÛJ£Ý.Chirurgia (Bucur),2021,116(4):399-408.
£Û12£Ý HUANG ZY,CHEN G,HAO XY,et al.Outcomes of non-anatomic liver resection for hepatocellular carcinoma in the patients with liver cirrhosis and analysis of prognostic factors£ÛJ£Ý.Langenbecks Arch Surg,2011,396(2):193-199.
£Û13£Ý ·½³Û»ª,ÕÅÅô,ÂÞ»ðÁé,µÈ.ÔöÇ¿ÏÖʵµ¼º½¼¼ÊõÁªºÏßÅßáݼÂÌ·Ö×ÓÓ«¹âÓ°ÏñÔÚÈýά¸¹Ç»¾µ¸ÎÇгýÊõÖеÄÓ¦ÓãÛJ£Ý.ÖлªÍâ¿ÆÔÓÖ¾,2019,57(8)£º578-584. FANG CH,ZHANG P,LUO HL,et al.Application of augmented-reality surgical navigation technology combined with ICG molecular fluorescence imaging in laparoscopic hepatectomy£ÛJ£Ý.Chin J Surg,2019,57(8)£º578-584.
£Û14£Ý TANAKA T,TAKATSUKI M,HIDAKA M,et al.Is a fluorescence navigation system with indocyanine green effective enough to detect liver malignancies£ÛJ£Ý.J Hepatobiliary Pancreat Sci,2014,21(3):199-204.
£Û15£Ý KUDO H,ISHIZAWA T,TANI K,et al.Visualization of subcapsular hepatic malignancy by indocyanine-green fluorescence imaging during laparoscopic hepatectomy£ÛJ£Ý.Surg Endosc,2014,28(8):2504-2508.
£Û16£Ý TERASAWA M,ISHIZAWA T,MISE Y,et al.Applications of fusion-fluorescence imaging using indocyanine green in laparoscopic hepatectomy£ÛJ£Ý.Surg Endosc,2017,31(12):5111-5118.
£Û17£Ý XIE F,HONG Y,SUN X,et al.Comparison of the value of conventional two-dimensional ultrasound,contrast-enhanced ultrasound and MSCT in early diagnosis of small hepatocellular carcinoma£ÛJ£Ý.Minerva Gastroenterol (Torino),2023,69(1):162-165.
£Û18£Ý HU Y,GUO W,MA J,et al.Application of indocyanine green fluorescence imaging combined with laparoscopic ultrasound in laparoscopic microwave ablation of liver cancer£ÛJ£Ý.Med Sci Monit,2022,28:e937832.
£Û19£Ý YE R,XIE Y,ZHONG D,et al.Effect of digital three-dimensional reconstruction technique combined with indocyanine green (ICG) excretion test for precision hepatectomy in primary liver cancer£ÛJ£Ý.Am J Transl Res,2023,15(5):3511-3520.
£Û20£Ý ÖлªÒ½Ñ§»áÊý×Öҽѧ·Ö»á,ÖйúҽʦЭ»á¸Î°©×¨ÒµÎ¯Ô±»á,ÖйúҽʦЭ»á¾«×¼Ò½Ñ§×¨ÒµÎ¯Ô±»á,µÈ.Ô­·¢ÐԸΰ©Èýά¿ÉÊÓ»¯¼¼Êõ²Ù×÷¼°ÕïÁƹ淶(2020°æ)£ÛJ£Ý.ÖлªÏû»¯Íâ¿ÆÔÓÖ¾,2020,19(09)£º897-918. Chinese Society of Digital Medicine,Liver Cancer Committee of Chinese Medical Doctor Association,Clinical Precision Medicine Committee of Chinese Medical Doctor Association,et al.Specification for technical operation and clinical application of three-dimensional visualization technology for primary liver cancer (2020 edition) £ÛJ£Ý.Chin J Dig Surg,2020,19(09)£º897-918.

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