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Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:

2024 05

Page:

948-953

Research Field:

Publishing date:

Info

Title:

Research progress on the mechanism of microsomal glutathione S-transferase 1 in malignant tumors

Author(s):

YANG Zheyan; SUN Zhengrong

Biobank,Shengjing Hospital of China Medical University,Liaoning Shenyang 110004,China.

Keywords:

microsomal glutathione S-transferase 1; malignant tumor; research progress

PACS:

R73-3

DOI:

10.3969/j.issn.1672-4992.2024.05.028

Abstract:

Microsomal glutathione S-transferase 1 (MGST1) is a common member of the glutathione S-transferase (GST) superfamily and the membrane associated proteins in glutathione metabolism (MAPEG) superfamily,it protects cell membranes from oxidative stress by catalyzing phase II detoxification of exogenous substances.Many studies have found that MGST1 is closely related to the occurrence and development of malignant tumors,which is expected to become a new molecular target for cancer therapy.This article reviews the research progress of MGST1 in malignant tumor.

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Memo

Memo:

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Last Update: 2024-01-30