|Table of Contents|

LncRNA MAFG-AS1:A potential biomarker and therapeutic target in malignancy

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2024 04
Page:
731-737
Research Field:
Publishing date:

Info

Title:
LncRNA MAFG-AS1:A potential biomarker and therapeutic target in malignancy
Author(s):
XIAO YananCHEN XuyuLI JieLI Juan
Department of Oncology,Second Affiliated Hospital of Nanjing Medical University,Jiangsu Nanjing 210011,China.
Keywords:
long non-coding RNALncRNA MAFG-AS1cancerbiomarkertherapeutic target
PACS:
R730
DOI:
10.3969/j.issn.1672-4992.2024.04.026
Abstract:
The regulatory role of long non-coding RNAs (LncRNAs) in tumor development has attracted extensive attention.LncRNA MAFG-AS1,a novel cancer-promoting LncRNA,is highly expressed in lung cancer,breast cancer,hepatocellular carcinoma and other tumors,and is closely related to malignant behaviors such as tumor cell proliferation,migration,and invasion.Moreover,a large amount of evidence has shown that up-regulation of LncRNA MAFG-AS1 was related to the clinicopathological stage and poor survival prognosis of cancer patients.In this paper,we systematically summarized the research on the expression,biological function,molecular mechanism,and clinical significance of LncRNA MAFG-AS1 in various tumors in recent years,and emphasized that LncRNA MAFG-AS1 can serve as a novel diagnostic and prognostic biomarker,and can be an important target for cancer treatment.

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Memo

Memo:
National Natural Science Foundation of China(No.81972278);国家自然科学基金面上项目(编号:81972278);拔尖人才研究项目(编号:LGY2019078)
Last Update: 1900-01-01