[1] WU T,DAI Y.Tumor microenvironment and therapeutic response [J].Cancer Lett,2017,387:61-68.
[2] KIRKALDY-WILLIS WH.Cystoscopy in the diagnosis and treatment of Bilharzia haematobium infection [J].Br J Surg,1946,34:189-194.
[3] 王子健.肠肿瘤相关巨噬细胞的极化调控血吸虫病结直肠癌的发生发展 [J/OL].皖南医学院,2020(2020-12-16)[2021-01-15].https://kns.cnki.net/KCMS/detail/detail.aspx?dbname=CMFD202101&filename=1020068591.nh.DOI:10.27374/d.cnki.gwnyy.2020.000182.
WANG ZJ.Polarization of intestinal tumor-associated macrophages regulate the occurrence and development of schistosomal colorectal cancer [J/OL].Wan Nan Medical College,2020(2020-12-16)[2021-01-15].https://kns.cnki.net/KCMS/detail/detail.aspx?dbname=CMFD202101&filename=1020068591.nh.DOI:10.27374/d.cnki.gwnyy.2020.000182.
[4] 戎泽印,黄陈.血吸虫肠病相关性结直肠癌的研究进展[J].现代肿瘤医学,2019,27(02):335-339.
RONG ZY,HUANG C.Research progress of colorectal cancer with schistosomiasis [J].Modern Oncology,2019,27(02):335-339.
[5] FANG Y,WU CY,CHEN Q,et al.SjE16.7 activates macrophages and promotes Schistosoma japonicum egg-induced granuloma development [J].Acta Trop,2015,149:49-58.
[6] LEE ERINNA F,CLARKE OLIVER B,EVANGELISTA MARCO,et al.Discovery and molecular characterization of a Bcl-2-regulated cell death pathway in schistosomes [J].Proc Natl Acad Sci USA,2011,108:6999-7003.
[7] DEMATEI ANDERSON,FERNANDES RUBEN,SOARES RAQUEL,et al.Angiogenesis in Schistosoma haematobium-associated urinary bladder cancer [J].APMIS,2017,125:1056-1062.
[8] EISSA SANAA,ZOHNY SAMIR F,ZEKRI ABDEL-RAHMAN N,et al.Diagnostic value of fibronectin and mutant p53 in the urine of patients with bladder cancer:impact on clinicopathological features and disease recurrence [J].Med Oncol,2010,27:1286-1294.
[9] CHEN LT,YU Y,LIU ET,et al.Schistosoma japonicum soluble egg antigen inhibits TNF-α-induced IL-34 expression in hepatic stellate cells [J].Parasitol Res,2019,118:551-557.
[10] BALKWILL FR,CAPASSO M,HAGEMANN T.The tumor microenvironment at a glance [J].Cell Sci,2012,125:5591-5596.
[11] HUANG HW,CHANG CC,WANG CS,et al.Association between inflammation and function of cell adhesion molecules influence on gastrointestinal cancer development [J].Cells,2021,10:67.
[12] KIM J,BAE JS.Tumor-associated macrophages and neutrophils in tumor microenvironment [J].Mediat Inflamm,2016,2016:6058147.
[13] NGWA VM,EDWARDS DN,PHILIP M,et al.Microenvironmental metabolism regulates antitumor immunity [J].Can Res,2019,79:4003-4008.
[14] TURAILIC S,LITCHFIELD K,XU H,et al.Insertion and deletion derived tumour-specific neoantigens and the immunogenic phenotype:a pan-cancer analysis [J].Lancet Oncol,2017,18:1009-1021.
[15] ZHU Y,CHEN M,ZHU T,et al.Critical steps to tumor metastasis:Alterations of tumor microenvironment and extracellular matrix in the formation of premetastatic and metastatic niche [J].Cell Biosci,2020,10:89.
[16] SELLNER F,THALHAMMER S,KLIMPFINGER M.Tumour evolution and seed and soil mechanism in pancreatic metastases of renal cell carcinoma [J].Cancers,2021,13:1342.
[17] SRINIVASAN ES,TAN AC,ANDERS CK,et al.Salting the soil:Targeting the microenvironment of brain metastases [J].Mol Cancer Ther,2021,20:455-466.
[18] PITT JM,MARABELLE A,EGGERMONT A,et al.Targeting the tumor microenvironment:removing obstruction to anticancer immune responses and immunotherapy [J].Ann Oncol,2016,27(8):1482-1492.
[19] MATOS AI,CARREIRA B,PERES C,et al.Nanotechnology is an important strategy for combinational innovative chemo-immunotherapies against colorectal cancer [J].J Control Release,2019,307:108-138.
[20] PEDDAREDDIGARI VG,WANG D,DUBOIS RN.The tumor microenvironment in colorectal carcinogenesis [J].Cancer Microenviron,2010,3(1):149-166.
[21] TZENG HT,SU CC,CHANG CP,et al.Rab37 in lung cancer mediates exocytosis of soluble ST2 andthus skews macrophages towards tumor-suppressing phenotype [J].Int J Cancer,2018,143:1753-1763.
[22] GORDON SIAMON,MARTINEZ FERNANDO O.Alternative activation of macrophages:mechanism and functions [J].Immunity,2010,32:593-604.
[23] WANG H,TIAN T,ZHANG JH.Tumor-associated macrophages (TAMs) in colorectal cancer (CRC):From mechanism to therapy and prognosis [J].Int J Mol Sci,2021,22:8470.
[24] ZHANG Q,HE Y,LUO N,et al.Landscape and dynamics of single immune cells in hepatocellular carcinoma [J].Cell,2019,179(4):829-845.
[25] MARTíNEZ VCTOR G,RUBIO CAROLINA,MAARTNEZ-FERNNEDZ MONICA,et al.BMP4 induces M2 macrophage polarization and favors tumor progression in bladder cancer [J].Clin Cancer Res,2017,23:7388-7399.
[26] 李佳鑫,孙燕.结直肠癌免疫微环境中肿瘤相关巨噬细胞的作用[J].中国肿瘤临床,2020,47(17):890-896.
LI JX,SUN Y.Role of tumor-associated macrophages in the immune microenvironment of colorectal cancer[J].Chinese Journal of Clinical Oncology,2020,47(17):890-896.
[27] MILLS CHARLES D.M1 and M2 macrophages:Oracles of health and disease [J].Crit Rev Immunol,2012,32:463-488.
[28] MURRAY PJ,ALLEN JE,BISWAS SK,et al.Macrophage activation and polarization:nomenclature and experimental guidelines [J].Immunity,2014,41(1):14-20.
[29] LEWIS CE,POLLARD JW.Distinct role of macrophages in different tumor microenvironments[J].Cancer Res,2006,66(2):605-612.
[30] QIN X,LIU CY,XIONG YL,et al.The clinical features of chronic intestinal schistosomiasis-related intestinal lesions [J].BMC Gastroenterol,2021,21:12.
[31] ZAGHLOUL MOHAMD S,ZAGHLOUL TAREK M,BISHR MAI K,et al.Urinary schistosomiasis and the associated bladder cancer:update [J].J Egypt Natl Canc Inst,2020,32:44.
[32] 韩连秀,杨江华.血吸虫病与结直肠肿瘤关系的研究现状[J].中国病原生物学,2018,13(02):210-212.
HAN LX,YANG JH.Study on the relationship between schistosomiasis and colorectal tumors [J].Journal of Pathogen Biology,2018,13(02):210-212.
[33] LAUREN B PEIFFER,SARAH L POYNTON,SARAH E ERNST,et al.Inflammation associated pathologies in a case of prostate schistosomiasis:Implications for a causal role in prostate carcinogenesis [J].The Prostate,2019,79:1316-1325.
[34] YANG YK,WANG Y.Role of epigenetic regulation in plasticity of tumor immune microenvironment[J].Front Immunol,2021,12:640369.
[35] ZHOU SL,ZHOU ZJ,HU ZQ,et al.Tumor-associated neutrophils recruit macrophages and T-regulatory cells to promote progression of hepatocellular carcinoma and resistance to sorafenib [J].Gastroenterology,2016,150(7):1646-1658.
[36] CAO X.Self-regulation and cross-regulation of pattern-recognition receptor signalling in health and disease[J].Nat Rev Immunol,2016,16(1):35-50.
[37] WAKISAKA N,HASEGAWA Y,YOSHIMOTO S,et al.Primary tumor-secreted lymphangiogenic factors induce pre-metastatic lymphvascular niche formation at sentinel lymph nodes in oral squamous cell carcinoma[J].PLoS One,2015,10(12):e0144056.
[38]TANG Y,SHEN Y,HONG Y,et al.miR-181a regulates the host immune response against Schistosoma japonicum infection through the TLR4 receptor pathway [J].Parasit Vectors,2021,14(1):548.
[39] BRITTANY-AMBER JACOBS,SHARON PRINCE,KATHERINE ANN SMITH.Gastrointestinal nematode-derived antigens alter colorectal cancer cell proliferation and migration through regulation of cell cycle and epithelial-mesenchymal transition proteins [J].Mol Sci,2020,21:7845.
[40] LIU J,ZHU L,WANG JB,et al.Schistosoma japonicum extracellular vesicle miRNA cargo regulates host macrophage functions facilitating parasitism [J].PLoS Pathog,2019,15:e1007817.
[41] VINNAKOTA K,ZHANG Y,SELYANESAN BC,et al.M2-like macrophages induce colon cancer cell invasion via matrix metalloproteinases [J].Cell Physiol,2017,232(12):3468-3480.
[42] MIRA E,LACALE RA,BUESA JM,et al.Secreted MMP9 promotes angiogenesis more efficiently than constitutive active MMP9 bound to the tumor cell surface [J].J Cell Sci,2004,117:1847-1857.
[43] HUANG CY,YU LC.Distinct patterns of interleukin-12/23 and tumor necrosis factor alpha synthesis by activated macrophages are modulated by glucose and colon cancer metabolites [J].Physiol,2020,63:7-14.
[44] LINDAU D,GIELEN P,KROESEN M,et al.The immunosuppressive tumour network:myeloid-derived suppressor cells,regulatory T cells and natural killer T cells[J].Immunology,2013,138:105-115.
[45] MBANELO EVARISTUS C,HSIUS MICHAEL H.Defining the pathways of urogenital schistosomiasis-associated urothelial carcinogenesis through transgenic and bladder wall egg injection models [J].Methods Mol Biol,2018,1655:67-76.
[46] BOTELHO MONICA CATARINA,MAHADAO JOSE CARLOS,BRINDLEY PAUL J,et al.Targeting molecular signaling pathways of Schistosoma haemotobium infection in bladder cancer [J].Virulence,2011,2:267-279.
[47]李江,黄志勇.肝癌免疫微环境与免疫治疗研究进展[J].临床外科杂志,2021,29(11):1089-1091.
LI J,HUANG ZY.Current status of the research on microenvironment-targeting therapy and immunotherapy for liver cancer[J].Journal of Clinical Surgery,2021,29(11):1089-1091.
[48] HU C,LI YZ,PAN D,et al.Schistosoma japonicuma microRNA exerts antitumor effects through inhibition of both cell migration and angiogenesis by targeting PGAM1 [J].Front Oncol,2021,11:652395.
[49] WONG WAIHAY J,RUHANGAZA DEOGRATIAS,MANIRAKIZA ALEXIS,et al.Concomitant classic Hodgkin lymphoma and schistosomiasis [J].Am J Hematol,2019,94:840-841.