|Table of Contents|

Imaging and pathological features of hepatic epithelioid hemangioendothelioma(16 cases)

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2023 06
Page:
1108-1112
Research Field:
Publishing date:

Info

Title:
Imaging and pathological features of hepatic epithelioid hemangioendothelioma(16 cases)
Author(s):
TANG Xing1; BAI Guoyan2; FU Xin3; LIU Yan4
1.Department of Radiology;3.Department of Pathology,the First Affiliated Hospital of Air Force Medical University (Xijing Hospital）,Shaanxi Xi'an 710032,China;2.Department of Clinical Laboratory,Shaanxi Provincial People's Hospital,Shaanxi Xi'an 710068,China;4.Department of Radiology,Gem Flower Changqing Xinglongyuan Hospital,Shaanxi Xi'an 710018,China.
Keywords:
hepatic epithelioid hemangioendothelioma; CT; MR; immunohistochemistry
PACS:
R735.7
DOI:
10.3969/j.issn.1672-4992.2023.06.024
Abstract:
Objective:To analyze the imaging and pathological features of hepatic epithelioid hemangioendothelioma (HEHE),in order to improve the ability of diagnosis and differential diagnosis of HEHE.Methods:A retrospective analysis was performed for computed tomography (CT),magnetic resonance (MR) images and pathological features of 16 patients who visit our hospital with pathologically confirmed HEHE.Results:There were 5 cases of single lesions.Multiple lesions were found in 11 cases.The lesions on CT plain scan showed low density and were mostly round or quasi-round.Multiple lesions were distributed under the right lobe of the liver capsule.MR plain T2 weighted image (T2WI) scan showed uneven high signal.T1 weighted image (T1WI) scan showed heterogeneous low signal.CT and MR enhancement scan showed the ring enhancement and progressive centripetal enhancement.Immunohistochemistry showed 16 cases were positive for CD31.15 cases were positive for CD34.12 cases were positive for ERG.Conclusion:CT and MR have a certain value in the examination of HEHE.The imaging features have certain characteristics,and can help the preoperative diagnosis,but preoperative differential diagnosis is difficult.The pathological examination is needed.

References:

［1］WEISS SW,ENZINGER FM.Epithelioid hemangioendothelioma:a vascular tumor often mistaken for a carcinoma［J］.Cancer,1982,50(5):970-981.
[2]STUDER LL,SELBY DM.Hepatic epithelioid hemangioendothelioma［J］.Archives of Pathology and Laboratory Medicine,2018,142(2):263-267.
[3]MEHRABI A,HOFFMANN K,WEISS KH,et al.Long term follow up after resection emphasizes the role of surgery in primary hepatic epithelioid hemangioendothelioma［J］.Annals of Surgery (Lond),2016,11:1-4.
[4]ELLEUCH N,DAHMANI W,AIDA BS,et al.Hepatic epithelioid hemangioendothelioma:A misdiagnosed rare liver tumor［J］.Presse Medicale,2018,47(2):182-185.
[5]GAN LU,CHANG R,JIN H,et al.Typical CT and MRI signs of hepatic epithelioid hemangioendothelioma［J］.Oncology Letters,2016,11(3):1699-1706.
[6]徐亚丹,王希,汪瀚韬,等.肝上皮样血管内皮瘤超声造影与增强磁共振表现的对比研究［J］.中华肝胆外科杂志,2017,23(2):82-86. XU YD,WANG X,WANG HT,et al.Comparative study of contrast enhanced ultrasound versus contrast enhanced MRI in hepatic epithelioid hemangioendothelioma［J］.Chinese Journal of Hepatobiliary Surgery,2017,23(2):82-86.
[7]WANG LR,ZHOU JM,ZHAO YM,et al.Clinical experience with primary hepatic epithelioid hemangioendothelioma:retrospective study of 33 patients［J］.World Journal of Surgery,2012,36(11):2677-2683.
[8]王小鹏,梁盼,李睿,等.CT征象及定量指标分析对肝上皮样血管内皮瘤与肝转移瘤的鉴别诊断［J］.中华肝胆外科杂志,2020,26(2):90-95. WANG XP,LIANG P,LI R,et al.CT imaging and quantitative analysis in the differential diagnosis of hepatic epithelioid hemangioendothelioma and hepatic metastasis［J］.Chinese Journal of Hepatobiliary Surgery,2020,26(2):90-95.
[9]赵越,龙世亮,田执南,等.肝上皮样血管内皮瘤的CT与MRI特征及病理基础［J］.CT理论与应用研究,2015,24(4):563-569. ZHAO Y,LONG SL,TIAN ZN,et al.The CT and MRI features of hepatic epithelioid hemangioendothelioma with the correlation of pathology［J］.Computerized Tomography Theory and Applications,2015,24(4):563-569.
[10]周丽莎,翟凤仪,董帜,等.肝脏上皮样血管内皮瘤CT和MRI表现［J］.临床放射学杂志,2015,34(3):402-405. ZHOU LS,ZHAI FY,DONG Z,et al.CT and MRI features of hepatic epithelioid hemangioendotheliomas［J］.Journal of Clinical Radiology,2015,34(3):402-405.
[11]BECHARA A.Decision making,impulse control and loss of willpower to resist drugs:a neurocognitive perspective［J］.Nature Neuroscience,2005,8(11):1458-1463.
[12]KIM KA,KIM KW,PARK SH,et al.Unusual mesenchymal liver tumors in adults:radiologic-pathologic correlation［J］.American Journal of Roentgenology,2006,187(5):W481-W489.
[13]赖日权,田野,冯晓冬,等.上皮样血管内皮瘤的临床病理分析［J］.中华病理学杂志,2001,30(3):177-179. LAI RQ,TIAN Y,FENG XD,et al.A clinicopathologic study on 9 cases of epithelioid hemangioendothelioma［J］.Chinese Journal of Pathology,2001,30(3):177-179.
[14]LYBURN ID,TORREGGIANI WC,HARRIS AC,et al.Hepatic epithelioid hemangioendothelioma:sonographic,CT,and MR imaging appearances［J］.American Journal of Roentgenology,2003,180(5):1359-1364.
[15]MEHRABI A,KASHFI A,FONOUNI H,et al.Primary malignant hepatic epithelioid hemangioendothelioma:a comprehensive review of the literature with emphasis on the surgical therapy［J］.Cancer,2006,107(9):2108-2121.
[16]SINGH A,SOOD N,PURI HK,et al.Primary hepatic epithelioid hemangioendothelioma:diagnostic dilemmas in cytology and histology［J］.Journal of Oncology Practice,2016,12(4):394-396.

Memo

Memo:
-
Last Update: 1900-01-01