|Table of Contents|

Predictive biomarkers of immune checkpoint inhibitor

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2023 04
Page:
774-778
Research Field:
Publishing date:

Info

Title:
Predictive biomarkers of immune checkpoint inhibitor
Author(s):
LIU MeiqiuGAO Quanli
The Affiliated Cancer Hospital of Zhengzhou University,Henan Zhengzhou 450008,China.
Keywords:
tumorimmune checkpoint inhibitorprognosisbiomarker
PACS:
R730.5
DOI:
10.3969/j.issn.1672-4992.2023.04.035
Abstract:
The study of immune checkpoint inhibitors(ICI)targeting programmed death receptor 1(PD-1)/programmed death receptor ligand 1(PD-L1)pathway is very hot,providing new hope for the treatment of a variety of patients with advanced cancer.However,the effective rate of ICI is still low.Non-target patients do not respond to it,and some patients will have special response patterns such as delayed response and pseudoprogression.At present,there is no accurate efficacy predictor that can make a judgment on the tumor response and prognosis of patients in advance,which greatly limits the clinical application of immune checkpoint inhibitors.In this paper,we briefly review the efficacy predictive markers commonly used and recently studied.

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