|Table of Contents|

Incidence and mortality of childhood leukemia in Shenyang,China from 2013 to 2019

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2023 03
Page:
539-543
Research Field:
Publishing date:

Info

Title:
Incidence and mortality of childhood leukemia in Shenyang,China from 2013 to 2019
Author(s):
TIAN Wei1; LI Xun2; YU Haiyang1; PAN Xiudan1
1.Shenyang Medical College,Liaoning Shenyang 110034,China;2.Shenyang Center for Disease Control and Prevention,Liaoning Shenyang 110031,China.
Keywords:
children; leukemia; incidence; mortality
PACS:
R733.7
DOI:
10.3969/j.issn.1672-4992.2023.03.029
Abstract:
Objective:To analyze the trend of morbidity and mortality of childhood leukemia in Shenyang,China from 2013 to 2019.Methods:The data of incidence and death of childhood leukemia aged 0~14 years old were obtained from Shenyang Cancer Registration and Reporting System and resident cause of death report.The constituent ratio,incidence rate,age-specific incidence rate,mortality rate and age-specific mortality rate were calculated and standardized by Chinese standard population in 2000.Joinpoint regression model was applied for trend analysis.Results:The incidence and standardized incidence of childhood leukemia in Shenyang increased from 0.90/100 000 and 1.34/100 000 in 2013 to 5.33/100 000 and 5.14/100 000 in 2019,respectively,and APC was 19.64% and 16.39%,respectively.Among them,the change trend of incidence rate had statistical significance (P＜0.05).The average annual increase in the incidence of females was 22.77%,and the trend was statistically significant (P＜0.05).The incidence of lymphoid leukemia increased from 0.60/100 000 in 2013 to 3.77/100 000 in 2019,with an APC of 35.84%,and the increasing trend was statistically significant (P＜0.05).In 2013,the mortality rate and standardized mortality rate of childhood leukemia in Shenyang were 1.50/100 000 and 1.06/100 000,respectively,the mortality rate and standardized mortality rate of childhood leukemia in 2019 were 1.11/100 000 and 1.21/100 000,respectively,and the APC were -3.80% and -2.53%,respectively.There were no significant trend changes (P＞0.05).The average annual decrease in mortality was 6.25% in men and the average annual increase in mortality was 7.07% in women,but the trends were not statistically significant (P＞0.05).Leukemia morbidity and mortality occurred in all age groups,with the highest incidence of 4.74/100 000 in the age group of 0~4 years old and the highest mortality of 1.93/100 000 in the age group of 10~14 years old.Conclusion:From 2013 to 2019,the mortality rate of childhood leukemia in Shenyang was relatively stable,and the incidence rate increased,especially in women and lymphoid leukemia,which should be highly concerned.

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