|Table of Contents|

Research progress of B7-H5/CD28H in the occurrence and development of malignant tumors

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2023 02
Page:
373-376
Research Field:
Publishing date:

Info

Title:
Research progress of B7-H5/CD28H in the occurrence and development of malignant tumors
Author(s):
WANG JunqiXU Feng
Department of General Surgery,Shengjing Hospital of China Medical University,Liaoning Shenyang 110004,China.
Keywords:
immunosuppressionsignaling pathwayB7-H5CD28Hmalignant tumorsimmunotherapy
PACS:
R730.231
DOI:
10.3969/j.issn.1672-4992.2023.02.035
Abstract:
B7-H5/CD28H is a newly discovered immunosuppressive signal pathway,which plays a role in the occurrence and development of malignant tumors by regulating T cells and NK cells functions,cell adhesion and angiogenesis.Moreover,the expression levels of B7-H5 and CD28H are closely related to the prognosis of malignant tumors.In this article,not only the structure and function of B7-H5 and CD28H but also the relationship between B7-H5/CD28H expression levels and the prognosis were reviewed,in order to explore the application prospect of this signaling pathway in the immunotherapy of malignant tumors.

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Memo

Memo:
辽宁省自然科学基金项目(编号:20180551193,2020-MS-181);盛京医院345人才工程计划(编号:40B)
Last Update: 1900-01-01