|Table of Contents|

Feasibility of ovarian sparing by non-coplanar IMRT radiotherapy for cervical cancer

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2023 01
Page:
140-143
Research Field:
Publishing date:

Info

Title:
Feasibility of ovarian sparing by non-coplanar IMRT radiotherapy for cervical cancer
Author(s):
DONG Shengnan1; 2; HUANG Yangyang2; YANG Jun3; CHENG Pinjing1
1.School of Nuclear Science and Technology,University of South China,Hunan Hengyang 421001,China;2.The Second Affiliated Hospital of Zhengzhou Universty,Henan Zhengzhou 450003，China;3The Third Affiliated Hospital of Zhengzhou Universty,Henan Zhengzhou 450052，China.
Keywords:
cervical cancer; ovarian sparing; non-coplanar IMRT
PACS:
R737.33
DOI:
10.3969/j.issn.1672-4992.2023.01.026
Abstract:
Objective:To study the feasibility of ovarian sparing by non-coplanar IMRT radiotherapy for cervical cancer.Methods:A total of 17 ovarian sparing patients with cervical cancer were selected.The IMRT plans for two groups were designed separately according to unified criteria,including the coplanar IMRT plans for ovarian sparing (group A),and non-coplanar IMRT plans for ovarian sparing(group B).Plan parameters of two groups were collected，and the γ passing rate was verified.Statistical analysis studies were performed.Results:All the plans for two groups met clinical requirements.The maximum dose of ovarian in group B was lower than group A(P＜0.05).For planing target volume(PTV),the conformity index(CI) and the homogeneity index(HI) of group B were better than group A(P＜0.05).The D5 of group A was higher than group B(P＜0.05),and the D95 of group B was higher than group A(P＜0.05).For organ at risk(OAR),V40 of bladder,Dmean of rectum,Dmax of small intestine,and V20 of left femoral head in group A were higher than group B(P＜0.05).There were no significant differences in V20,V30,Dmean of bladder,V30,V40 of rectum,V40 of small intestine,V10,V20,V30 of right femoral head，V10,V30 of left femoral head and Dmax of bone marrow between group A and group B(P＞0.05).The number of MU for group B was higher than group A.With the criterion of 3%/2 mm and threshold of 10%,the γ passing rate of the group A was higher than group B (P＜0.05).Conclusion:Both group A and group B could achieve ovarian sparing,but the non-coplanar IMRT plan performs better,with better dose distribution in PTV and less impact on organs at risk.

References:

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Memo

Memo:
河南省医学科技攻关计划联合共建项目（编号：LHGJ20210407）;河南省科技攻关项目（社会发展领域）（编号：182102310700）
Last Update: 2022-11-30