|Table of Contents|

Research progress of the mechanism and clinical application of miR-335 in the malignant tumor

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2022 04
Page:
721-724
Research Field:
Publishing date:

Info

Title:
Research progress of the mechanism and clinical application of miR-335 in the malignant tumor
Author(s):
LIU Xueting; WANG Ying; SONG Jiayu; WANG Yuan; ZHANG Yunyan
Laboratory of Gynecological Radiotherapy,Harbin Medical University Cancer Hospital,Heilongjiang Harbin 150001,China.
Keywords:
miRNA; miR-335; tumor; target gene
PACS:
R730
DOI:
10.3969/j.issn.1672-4992.2022.04.035
Abstract:
The miRNAs are a large class of non-coding single-stranded RNAs with the length of 19~25 nucleotides,whose sequence is highly conserved in human.The miRNAs play a significant role in cellular physiological activity.we draw your attention to one such miRNA,miR-335 that exerts a regulatory influence on malignant tumors.On the one hand,overexpression of miR-335 can inhibit proliferation,invasion and migration of tumor cell.On the other hand,it can also increase the sensitivity of radiotherapy and chemotherapy.Moreover,miR-335 might be a potential biomarker of cancer.Overall,our review highlights the regulation and effects of miR-335 in malignant tumors,and explores the mechanism and clinical application of miR-335 in cancer from the aspects of gene expression,clinical diagnosis,treatment and prognosis.

References:

[1]KOMOLL RM,HU Q,OLAREWAJU O,et al.MicroRNA-342-3p is a potent tumour suppressor in hepatocellular carcinoma［J］.J Hepatol,2021,74:122-134.
[2]BLANCO-DOMNGUEZ R,SNCHEZ-DAZ R,DE LA FUENTE H,et al.A novel circulating microRNA for the detection of acute myocarditis［J］.N Engl J Med,2021,384:2014-2027.
[3]SHI CY,KINGSTON ER,KLEAVELAND B,et al.The ZSWIM8 ubiquitin ligase mediates target-directed microRNA degradation［J］.Science,2020,370:112-126.
[4]DONG Y,LIU Y,JIANG A,et al.MicroRNA-335 suppresses the proliferation,migration,and invasion of breast cancer cells by targeting EphA4［J］.Mol Cell Biochem,2018,439:95-104.
[5]SWELLAM M,MAHMOUD MS,HASHIM M,et al.Clinical aspects of circulating miRNA-335 in breast cancer patients:A prospective study［J］.J Cell Biochem,2019,120:8975-8982.
[6]BAKHTARI N,MOZDARANI H,SALIMI M,et al.Association study of miR-22 and miR-335 expression levels and G2 assay related inherent radiosensitivity in peripheral blood of ductal carcinoma breast cancer patients［J］.Neoplasma,2021,68:190-199.
[7]HAO J,LAI M,LIU C.Expression of miR-335 in triple-negative breast cancer and its effect on chemosensitivity［J］.J Buon,2019,24:1526-1531.
[8]ALMANZA G,RODVOLD JJ,TSUI B,et al.Extracellular vesicles produced in B cells deliver tumor suppressor miR-335 to breast cancer cells disrupting oncogenic programming in vitro and in vivo［J］.Sci Rep,2018,8:17581.
[9]WANG X,XIAO H,WU D,et al.miR-335-5p regulates cell cycle and metastasis in lung adenocarcinoma by targeting CCNB2［J］.Onco Targets Ther,2020,13:6255-6263.
[10]DU W,TANG H,LEI Z,et al.miR-335-5p inhibits TGF-β1-induced epithelial-mesenchymal transition in non-small cell lung cancer via ROCK1［J］.Respir Res,2019,20:225.
[11]LIU J,YAO L,ZHANG M,et al.Downregulation of LncRNA-XIST inhibited development of non-small cell lung cancer by activating miR-335/SOD2/ROS signal pathway mediated pyroptotic cell death［J］.Aging (Albany NY),2019,11:7830-7846.
[12]HUO W,ZHANG M,LI C,et al.Correlation of microRNA-335 expression level with clinical significance and prognosis in non-small cell lung cancer［J］.Medicine (Baltimore),2020,99:e21369.
[13]MU L,ZHAO H,YANG Y,et al.Long noncoding RNA NEAT1 aggravates sorafenib-resistance in non-small cell lung cancer via regulating miRNA-335/c-Met［J］.J Buon,2021,26:345-352.
[14]ZHOU X,YOU M,WANG F,et al.Multifunctional graphdiyne-cerium oxide nanozymes facilitate microRNA delivery and attenuate tumor hypoxia for highly efficient radiotherapy of esophageal cancer［J］.Adv Mater,2021,10:7812-7819.
[15]WU J,HUANG J,KUANG S,et al.Synergistic microRNA therapy in liver fibrotic rat using MRI-visible nanocarrier targeting hepatic stellate cells［J］.Advanced Science,2019,6:1-5.
[16]ZARE A,AHADI A,LARKI P,et al.The clinical significance of miR-335,miR-124,miR-218 and miR-484 downregulation in gastric cancer［J］.Mol Biol Rep,2018,45:1587-1595.
[17]GAO Y,WANG Y,WANG X,et al.miR-335-5p suppresses gastric cancer progression by targeting MAPK10［J］.Cancer Cell Int,2021,21:71.
[18]YAN Z,XIONG Y,XU W,et al.Identification of hsa-miR-335 as a prognostic signature in gastric cancer［J］.PLoS One,2012,7:e40037.
[19]ZHANG D,YANG N.MiR-335-5p inhibits cell proliferation,migration and invasion in colorectal cancer through downregul ating LDHB［J］.J Buon,2019,24:1128-1136.
[20]VICKERS MM,BAR J,GORN-HONDERMANN I,et al.Stage-dependent differential expression of microRNAs in colorectal cancer:potential role as markers of metastatic disease［J］.Clin Exp Metastasis,2012,29:123-132.
[21]SIEGEL RL,MILLER KD,JEMAL A.Cancer statistics,2020［J］.CA Cancer J Clin,2020,70:7-30.
[22]ZHANG JK,LI YS,ZHANG CD,et al.Up-regulation of CRKL by microRNA-335 methylation is associated with poor prognosis in gastric cancer［J］.Cancer Cell Int,2017,17:28.
[23]LIANG H,ZHANG C,GUAN H,et al.LncRNA DANCR promotes cervical cancer progression by upregulating ROCK1 via sponging miR-335-5p［J］.J Cell Physiol,2019,234:7266-7278.
[24]LI R,WANG Y,XU Y,et al.Silencing the long noncoding RNA,TINCR,a molecular sponge of miR-335,inhibits the malignant phenotype of epithelial ovarian cancer via FGF2 suppression［J］.Int J Oncol,2019,55:1110-1124.
[25]WANG S,LI Y,SUN S,et al.Sp1 promotes ovarian cancer cell migration through repressing miR-335 expression［J］.Biochem Biophys Res Commun,2020,524:211-216.
[26]LIU R,GUO H,LU S.MiR-335-5p restores cisplatin sensitivity in ovarian cancer cells through targeting BCL2L2［J］.Cancer Medicine,2018,7:4598-4609.
[27]LI HW,LIU J.Circ_0009910 promotes proliferation and metastasis of hepatocellular carcinoma cells through miR-335-5p/ROCK1 axis［J］.Eur Rev Med Pharmacol Sci,2020,24:1725-1735.
[28]YANG X,SONG H,ZI Z,et al.Circ_0005075 promotes hepatocellular carcinoma progression by suppression of microRNA-335［J］.J Cell Physiol,2019,234:21937-21946.
[29]WANG F,LI L,PIONTEK K,et al.Exosome miR-335 as a novel therapeutic strategy in hepatocellular carcinoma［J］.Hepatology,2018,67:940-954.
[30]YANG JH,LIN LK,ZHANG S.Epigenetic silencing of microRNA-335 contributes to nasopharyngeal carcinoma metastasis［J］.Am J Otolaryngol,2020,41:102302.
[31]YU Y,WANG L,LI Z,et al.Long noncoding RNA CRNDE functions as a diagnostic and prognostic biomarker in osteosarcoma,as well as promotes its progression via inhibition of miR-335-3p［J］.J Biochem Mol Toxicol,2021,9:27-31.
[32]WANG J,HE Z,XU J,et al.Long noncoding RNA LINC00941 promotes pancreatic cancer progression by competitively binding miR-335- 5p to regulate ROCK1-mediated LIMK1/Cofilin-1 signaling［J］.Cell Death Dis,2021,12:36.
[33]YANG F,TANG Z,DUAN A,et al.Long noncoding RNA NEAT1 upregulates survivin and facilitates gallbladder cancer progression by sponging microRNA-335［J］.Onco Targets Ther,2020,13:2357-2367.
[34]ZHANG P,YANG X,WANG L,et al.Overexpressing miR-335 inhibits DU145 cell proliferation by targeting early growth response 3 in prostate cancer［J］.Int J Oncol,2019,54:1981-1994.
[35]CHEN D,CHEN T,GUO Y,et al.Platycodin D (PD) regulates LncRNA-XIST/miR-335 axis to slow down bladder cancer progression in vitro and in vivo［J］.Exp Cell Res,2020,396:112281.

Memo

Memo:
National Natural Science Foundation of China(No.81672584）；国家自然科学基金（编号：81672584）
Last Update: 1900-01-01