|Table of Contents|

Research progress of pigment epithelium-derived factor in lung cancer

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2022 03
Page:
584-587
Research Field:
Publishing date:

Info

Title:
Research progress of pigment epithelium-derived factor in lung cancer
Author(s):
LIN Huan1; NIU Chunlai2; NING Yunye1; LIU Jian1; FANG Chen1; ZOU Yitan1
1.Department of Respiratory and Critical Care Medicine,Changhai Hospital Affiliated to Naval Medical University,Shanghai 200433,China;2.Department of Rehabilitation Medicine,Huadong Hospital Affilated to Fudan University,Shanghai 200040,China.
Keywords:
pigment epithelium-derived factor; lung cancer; mechanism
PACS:
R734.2
DOI:
10.3969/j.issn.1672-4992.2023.03.039
Abstract:
Lung cancer is the most common cause of cancer mortality worldwide.Many studies have found that the pigment epithelium-derived factor (PEDF) expressed in a wide variety of tumor cells is reduced.PEDF can inhibit the proliferation of tumor cells,promote the apoptosis of cell tumors,inhibit the invasion and metastasis of tumor cells,and inhibit the formation of tumor neovascularization,etc.The supplement of PEDF have a broad application prospect in the treatment of multiple types of tumors.This article reviews the expression and biological function of pigment epithelial-derived factors in diagnosis and treatment of lung cancer.

References:

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长海医院院级科研项目（编号：2018QNB010）
Last Update: 2022-12-30