|Table of Contents|

The role and mechanism of lncRNA in metastasis of esophageal squamous cell carcinoma

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2022 01
Page:
150-155
Research Field:
Publishing date:

Info

Title:
The role and mechanism of lncRNA in metastasis of esophageal squamous cell carcinoma
Author(s):
WANG Yixuan12LU Ning1ZHANG Xiaoqing1LI Minna1ZHOU Ying3ZHANG Lingmin1ZHANG Mingxin13
1.The First Affiliated Hospital of Xi'an Medical University,Shaanxi Xi'an 710077,China;2.Xi'an Medical University,Shaanxi Xi'an 710000,China;3.Shaanxi University of Chinese Medicine,Shaanxi Xianyang 712046,China.
Keywords:
esophageal squamous cell carcinomametastasislong non-coding RNA
PACS:
R735.1
DOI:
10.3969/j.issn.1672-4992.2022.01.033
Abstract:
Esophageal squamous cell carcinoma(ESCC)is highly aggressive and metastatic.It is prone to metastasis at an early stage and has a poor prognosis.It is one of the most common cancers worldwide.Long non-coding RNA(lncRNA),as a transcriptional regulator,can regulate a variety of genomic and cellular processes,such as cell proliferation,migration,and invasion.lncRNA has also been shown to be involved in regulating signal pathways related to tumor metastasis.A large number of studies have tried to reveal the important role of lncRNA in the occurrence and metastasis of esophageal cancer.This article focuses on the epigenetics,gene expression level and as a competitive endogenous RNA pathway of lncRNA,and reviews the research progress of lncRNA in ESCC metastasis,which is of great significance for the prognosis monitoring and targeted therapy of ESCC patients.

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Memo

Memo:
陕西省自然科学基础研究计划(编号:2018JM7090);陕西省教育厅专项科研计划项目(编号:19JK0765);陕西省西安市科技计划项目[编号:2019114713YX002SF035(6)]
Last Update: 2021-12-02