[1] Kim CK,He P,Bialkowska AB,et al.SP and KLF transcription factorsin digestive physiology and diseases[J].Gastroenterology,2017,152(8):1845-1875.
[2] Pollak NM,Hoffman M,GoldbergI J,et al.Krüppel-like factors:Crippling and un-crippling metabolic pathways[J].JACC BasicTranslSci,2018,3(1):132-156.
[3] Farrugia MK,Sharma SB,Lin CC,et al.Regulation of anti-apoptotic signaling by Krüppel-like factors 4 and 5 mediates lapatinib resistance in breastcancer[J].Cell Death Dis,2015,6(3):e1699.
[4] Siegel RL,Miller KD,Jemal A.Cancer statistics,2018[J].CA Cancer J Clin,2018,68(01):7-30.
[5] Nandan MO,Ghaleb AM,Liu Y,et al.Inducibleintestine-specific deletion of Krüppel-like factor 5 is characterized by a regenerative response in adult mouse colon[J].Dev Biol,2014,387(2):191-202.
[6] Nakaya T,Ogawa S,Manabe I,et al.KLF5 regulates the integrity and oncogenicity of intestinalstem cells[J].Cancer Res,2014,74(10):2882-2891.
[7] Bialkowska AB,Liu Y,Nandan MO,et al.A colon cancer-derived mutant of Kruppel-like factor 5 (KLF5) is resistant to degradation by glycogen synthase kinase 3beta (GSK3beta) and the E3 ubiquitin ligase F-box and WD repeat domain-containing 7alpha (FBW7alpha)[J].J Biol Chem,2014(289):5997-6005.
[8] Lin J,Yu X,Yang X,et al.High incidence of incidental prostate cancerin transurethral resection of prostate specimens in China.The value of pathologic review[J].Anal Quant Cytopathol Histpathol,2016,38(1):31-37.
[9] Tokudome S,Ando R,Koda Y.Discoveries and application of prostate-specific antigen,and some proposals to optimize prostate cancer screening[J].Cancer Manag Res,2016,10(8):45-47.
[10] Xing C,Ci X,Sun X,et al.Klf5 dele-tion promotes Pten deletion-initiated luminal-type mouseprostatetumorsthroughmultipleoncogenicsignaling pathways[J].Neopla-sia,2014,16(11):883-99.
[11] Luan Y,Wang P.FBW7-mediated ubiquitination and degradation of KLF5[J].World J Biol.Chem,2014,5(02):216-223.
[12] Nakajima Y,Akaogi K,Suzuki T,et al.Estrogen regulates tumor growth through anonclassical pathway that includes the transcription factors ERbeta and KLF5[J].Sci Signal,2011,4(168):ra22.
[13] Li X,Zhang B,Wu Q,et al.Interruption of KLF5 acetylation converts its function from tumor suppressor to tumor promoter in prostate cancer cells[J].Int J Cancer,2015,136(3):536-546.
[14] Xing C,Ci X,Sun X,et al.Klf5 dele-tion promotes Pten deletion-initiated luminal-type mouse prostate tumorsthrough multiple oncogenic signaling pathways[J].Neoplasia,2014,16(11):883-899.
[15] Guo P,Dong XY,Zhao KW,et al.Estrogen-induced interaction between KLF5 and estrogen receptor(ER)suppresses the function of ER in ER-positive breast cancer cells[J].Int J Cancer,2010,126(1):81-89.
[16]Liu R,Shi P,Zhou Z,et al.Krüpple-like factor 5 is essential for mammary gland development and tumorigenesis[J].J Patho,2018,doi:10.1002 / path.5153.
[17] Liu R,Zhou Z,Zhao D,et al.The induction of KLF5 transcription factor by progesterone contributes to progesterone-induced breast cancer cell proliferation and dedifferentiation[J].Mol Endocrinol,2011,25(7):1137-1144.
[18] Zhang XY,Zhang PY.Gastric cancer:Somatic genetics as a guide to therapy[J].J Med Genet,2017,54(5):305.
[19]Chen S,Rao H,Liu J,et al.Lymph nodes ratio based nomogram predicts survival of resectable gastric cancer regardless of the number of examined lymph nodes [J].Oncotarget,2017,8(28):45585.
[20]Okimoto RA,Breitenbuecher F,Olivas VR,et al.Inactivation of capicua drives cancer metastasis[J].Nature genetics,2017,49(1):87.
[21] Rocken C.Molecular classification of gastric cancer[J].Expert Rev Mol Diagn,2017,17(3):293-301.
[22] Kwak MK,Lee HJ,Hur K,et al.Expression of Kruppel-like factor 5 in human gastric carcinomas[J].J.Cancer Res Clin Oncol,2008,134(2):163-167.
[23] Soon MS,Hsu LS,Chen CJ,et al.Expression of Kruppel-like factor 5 in gastric cancer and its clinical correlation in Taiwan[J].Virchows Arch,2011,459(2):161-166.
[24] Akhavan-Niaki H,Samadani AA.Molecular insight in gastric cancer induction:An overview of cancer stemness genes[J].Cell Biochem Biophys,2014,68(3):463-473.
[25] Ouyang Y,Yuan W,Qiu S,et al.MicroRNA-153 functions as a tumor suppressor in gastric cancer via targeting Kruppel-like factor 5[J].Exp Ther Med,2018,16(2):473-482.
[26] Siegel RL,Miller KD,Jemal A.Cancer statistic[J].CA Cancer J Clin,2017(67):7-30.
[27] Wong MCS,Lao XQ,Ho K-F,et al.Incidence and mortality of lung cancer:Globaltrends and association with socioeconomic status[J].Sci Rep,2017(7):14300.
[28] Li X,Liu X,Xu Y,et al.KLF5 promotes hypoxia-induced survival and inhibits apoptosis in non-small cell lung cancer cells via HIF-1alpha[J].Int J Oncol,2014,45(4):1507-1514.
[29] Shimamura T,Imoto S,Shimada Y,et al.A novelnetwork profiling analysis reveals system changes in epithelial-mesenchymal transition[J].PLoS One,2011,6(6):e20804.
[30] Meyer SE,Hasenstein JR,Baktula A,et al.Kruppel-like factor 5 is not required for K-RasG12D lung tumorigenesis,butrepresses ABCG2 expression and is associated with better disease-specific survival[J].Am J Pathol,2010(177):1503-1513.