|Table of Contents|

Research progress of transcription factor KLF 5 in tumor

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2020 06
Page:
1036-1039
Research Field:
Publishing date:

Info

Title:
Research progress of transcription factor KLF 5 in tumor
Author(s):
Qin HaidanZhao YanbinWang Yan
Department of Medical Oncology,the Affiliated Tumor Hospital of Harbin Medical University,Heilongjiang Harbin 150001,China.
Keywords:
Krüppel like factor 5(KLF 5)KLF familytumors
PACS:
R730.231
DOI:
10.3969/j.issn.1672-4992.2020.06.037
Abstract:
Krüppel like factor 5(KLF 5) belongs to the family of transcription factors containing zinc finger and is involved in the regulation of the expression of multiple genes,thereby affecting the multiple functions of cells,such as stem cells self-renewal,cell proliferation,differentiation and apoptosis.KLF 5 has received increasing attention as an important transcription factor and potential drug target.In this review,we describe the characteristics of the KLF5 and KLF families and their progress in related tumors.

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Last Update: 2020-01-21