|Table of Contents|

Clinicopathological analysis of malignant solitary fibrous tumor and literature review

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2020 04
Page:
635-638
Research Field:
Publishing date:

Info

Title:
Clinicopathological analysis of malignant solitary fibrous tumor and literature review
Author(s):
Liu Tianyi; Zhong Lei
Department of Pathology,The 2nd Affiliated Hospital of Harbin Medical University,Heilongjiang Harbin 150086,China.
Keywords:
malignant solitary fibrous tumor; clinicopathology; differential diagnosis
PACS:
R730.2
DOI:
10.3969/j.issn.1672-4992.2020.04.026
Abstract:
Objective：To investigate the clinicopathologic characteristics,differential diagnosis of malignant solitary fibrous tumor.Methods:Nine cases of MSFT were reported.The clinical features,immunohistochemical analysis and imaging appearance were observed,and sacro-literatures were reviewed.Results:Among the 9 patients,6 were male,and 3 were female.The average age of 49.7 in males and 48.3 in females.The average diameter of the tumor was 9.39 cm.Histologically the tumor was composed of areas of altemating hypercellularity and hypocellularity.In some areas,hemangiopericytoma-like structure was present.The tumor cells were spindleshaped with marked nuclear atypia and increased mitotic activity.Immunohistochemically,STAT6 and Vimentin were always positive,CD34,BCL-2,CD99 were different degree positive.Conclusion:Diagnosis of MSFT mainly relies on morphologic features and immunohistochemistry.Differential diagnosis includes spindle-shaped cellular mesenchymal tumors.The prognosis of MSFT is poor and tends to recur and even metastasize.The major treatment is to completely resect it by operation and long-term clinical follow-up is necessary.

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Memo

Memo:
黑龙江省自然科学基金（编号：H2016024）
Last Update: 2019-12-26