|Table of Contents|

Correlation analysis between serum superoxide dismutase and nutritional status in patients with colorectal cancer

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2020 04
Page:
606-610
Research Field:
Publishing date:

Info

Title:
Correlation analysis between serum superoxide dismutase and nutritional status in patients with colorectal cancer
Author(s):
Zhang Lili1Chang Tingmin1Zhang Chaoxian1Han Yu1Zhang Lanfang1Zhao Yingzheng2
1.Department of Gastroenterology,the First Affiliated Hospital of Xinxiang Medical University,Henan Xinxiang 453000,China;2.School of Public Health,Xinxiang Medical University,Henan Xinxiang 453000,China.
Keywords:
colorectal cancersuperoxide dismutasenutritional status
PACS:
R735.3
DOI:
10.3969/j.issn.1672-4992.2020.04.019
Abstract:
Objective:To investigate the correlation of serum superoxide dismutase and nutrition level in colorectal cancer patients.Methods:From July 2015 to July 2018,120 cases of colorectal cancer(CRC) patients and 86 cases of intestinal polyps were enrolled in our hospital.Serum SOD level and nutritional indexes such as TP,ALB,PA,HGB and LY were compared between the two groups.The risk factors of decreased nutritional level in patients with colorectal cancer were analyzed by multiple factors,and the relationship between serum SOD level and each nutritional index was analyzed.Results:The indexes of SOD,ALB,HGB and LY in the intestinal polyp group were significantly higher than those in the colorectal cancer group(P<0.05).The indexes of SOD,ALB and HGB in patients with colorectal cancer NRS score<3 were significantly higher than those in the NRS score=3 patients(P<0.05).Risk factors for decreased nutritional status in patients included low SOD,low ALB and low HGB(P<0.05).Correlation analysis showed that serum TP,ALB,PA,HGB,LY and other indicators of colorectal cancer were positively correlated with SOD(P<0.05).Conclusion:The level of serum SOD and nutritional status of patients with colorectal cancer were significantly decreased,and the later the disease stage was,the greater the extent of decline was.The nutritional status of the patients was positively correlated with the serum SOD level.

References:

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Memo

Memo:
National Natural Science Foundation of China(No.81773399);国家自然科学基金(编号:81773399)
Last Update: 2019-12-26