|Table of Contents|

Clinical study of intensity-modulated radiotherapy combined with local endogenetic thermotherapy for malignant tumor patients with metastatic bone pain

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2019 22
Page:
4069-4073
Research Field:
Publishing date:

Info

Title:
Clinical study of intensity-modulated radiotherapy combined with local endogenetic thermotherapy for malignant tumor patients with metastatic bone pain
Author(s):
Yu Jiao1; Tian Yingxuan2; Peng Jianmei3; Yu Min4
1.Department of Radiation Oncology;2.Department of Respiration in the Aged;3.Department of B-Ultrasound Room;4.Department of Medical Oncology,People's Hospital of Shaanxi Province,Shaanxi Xi'an 710068,China.
Keywords:
intensity-modulated radiotherapy; local endogenetic thermotherapy; bone metastasis of malignant tumor; pain
PACS:
R738.1
DOI:
10.3969/j.issn.1672-4992.2019.22.031
Abstract:
Objective:To observe the recent efficacy of intensity-modulated radiotherapy (IMRT) combined with local endogenetic thermotherapy in the treatment of metastatic bone pain in malignant tumor patients.Methods:A total of 92 malignant tumor patients with metastatic bone pain were randomly divided into the experimental group (46 cases) and the control group (46 cases).The control group were treated by IMRT,the experimental group received local endogenetic thermotherapy within 1 hour after IMRT.The change of pain,life quality and activity ability before and after radiotherapy,number of breakout pain and adverse reaction were compared between two groups.Results:The NRS and activity ability of two groups after radiotherapy were all lower and KPS was higher than those before radiotherapy (P＜0.05),and the change in the experimental group were more significant (P＜0.05).The marked effective rate and total effective rate of NRS,KPS and activity ability improvement in experimental group were significantly better than those in the control group (P＜0.05).The number of breakout pain in the experimental group was significantly less than that in the control group (P＜0.05).The adverse reactions had no significant difference in two groups (P＞0.05).Conclusion:The clinical efficacy of IMRT combined with local endogenetic thermotherapy in the treatment of metastatic bone pain in malignant tumor patients is significantly,which can obviously relieve pain,improve life quality and activity ability,reduce the number of breakout pain,and do not increase the adverse reactions,so it is worthy of promotion in clinic.

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陕西省重点研发计划项目（编号：2017SF-146）；陕西省自然科学基础研究项目(编号：2014JM2-8167,2018JM7044）；陕西省卫生计生委科研项目（编号：2016D036）；陕西省呼吸工程疾病研究中心科研项目资助（编号：16SXK）；陕西省中医药管理局科研项目（编号：15-JC020,JCPT039）；陕西省科技厅社会发展重点研究项目(编号：2017SF-199)；西安市科技局社发攻关项目［编号：2016047SF/YX03(4)］
Last Update: 1900-01-01