|Table of Contents|

Comparison of dosimetry and radiation injury of the supine position and prone position in early left-breast cancer after breast conserving surgery

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2019 04
Page:
650-653
Research Field:
Publishing date:

Info

Title:
Comparison of dosimetry and radiation injury of the supine position and prone position in early left-breast cancer after breast conserving surgery
Author(s):
Huang Wei; Ma Jun; Yu Dahai; Song Wei; Huang Teng
Radiotherapy Department of Jiangsu Provincial Hospital of Traditional Chinese Medicine，Jiangsu Nanjing 210000,China.
Keywords:
breast cancer; breast conserving surgery; supine position; prone position; radiation injury
PACS:
R737.9
DOI:
10.3969/j.issn.1672-4992.2019.04.027
Abstract:
Objective:By comparing the differences in the dosimetry and radiation injuries of two different positions in the treatment plan of supine position and prone position in the early left-breast( L-breast) cancer after breast conserving surgery,to provide the basis for the clinical selection of suitable postural fixation.Methods:A total of 36 patients with early left breast cancer receiving breast conserving surgery,were selected,including 18 patients with supine radiotherapy and 18 patients with prone radiotherapy.The radiotherapy plans were all breast doses 50 Gy/25 f,2 Gy/f,5 f/w，and the sequential boost doses 10 Gy/5 f,2 Gy/f,5 f/w.To assess the difference between the dose of organs at risk and the radiation injury with different position.Results:The following indicators compared the two groups were statistically significant(P＜0.05):Left lung Dmean,V5,V20,heart Dmean,V30.Left lung Dmean（721.5±11.6）cGy,V5（20.4±1.4）%,V20（15.3±6.5）%,heart Dmean（468.6±60.4）cGy,V30（7.4±5.6）% in prone group.Left lung Dmean（632.4±38.6）cGy,V5（35.5±1.3）%,V20（21.2±7.9）%，heart Dmean（532.2±17.9）cGy,V30（9.1±2.3）% in supine group.In the two groups,2-year local recurrence rates were 5.6%(1/18) and 0%(0/18) respectively,no distant metastasis was found.The local control rate were 94.4% and 100%,the 2-year survival rate was 100%.There was no statistically significant difference between the two groups (P＞0.05).In the aspect of radiation injury,in both groups thare was no acute radiation injury of the lung and heart,and the skin reaction was all 1 stage skin reaction,there was no skin reaction of level 2 or above.There was no significant difference between the skin reaction of the prone and supine groups.Conclusion:Compared to the supine radiotherapy,prone position radiotherapy is better for the protection of left lung and heart,and the skin damage is not inferior to the supine group in the absence of reduced survival.

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Memo

Memo:
National Natural Science Foundation of China(No.81703758);国家自然科学基金（编号：81703758）
Last Update: 1900-01-01