|Table of Contents|

Morphological analysis of bone marrow invasion in 60 cases of follicular lymphoma

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2019 03
Page:
480-485
Research Field:
Publishing date:

Info

Title:
Morphological analysis of bone marrow invasion in 60 cases of follicular lymphoma
Author(s):
Peng Xiongwen1; Shen Leyuan2; Lin Hang2; Qiu Xiaohui3; Zhang Shuping3
1.Department of Hematologic Neoplasms；2.Department of Medical Examination；3.Department of Laboratory，Sun Yat-sen University Cancer Center，Guangdong Guangzhou 510060，China.
Keywords:
follicular lymphoma; bone marrow invasion; morphological classification; immunophenotyping
PACS:
R733.4
DOI:
10.3969/j.issn.1672-4992.2019.03.030
Abstract:
Objective：Morphological analysis of the lymphoma cells in the bone marrow of follicular lymphoma was carried out to summarize the morphological characteristics，which provided certain references for the pathologist of bone marrow of follicular lymphoma. Methods：From 2013 to 2018 clinical data were retrospectively analyzed in 565 cases of patients with follicular lymphoma with lymph node biopsy pathology and select 60 cases of patients with bone marrow involvement were selected，then the bone marrow smears were observed.According to its morphological characteristics of tumor cells，the common characteristic was found out.Results：This group of 60 cases of follicular lymphoma tumor cells in bone marrow smear morphological characteristics will be divided into five types，including small non-split lymphocyte type(38.3%)，small split lymphocyte type(31.7%)，prolymphocytic type(5.0%)，primordial lymphocyte type(5.0%)，and large B-lymphocyte type(20.0%).Conclusion：Cases of follicular lymphoma involving the marrow can be divided into five types through the observation of tumor cells form，among them small non- split lymphocyte and small split lymphocyte accounts for the most common(70.0%).There are obvious characteristics in each type of the tumor cells，and important pathologic and clinical significance.

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Last Update: 2018-12-29