|Table of Contents|

Anti-angiogenesis therapy with bevacizumab as maintenance treatment in a patient with small cell lung cancer:A case report and literature review

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2019 03
Page:
411-415
Research Field:
Publishing date:

Info

Title:
Anti-angiogenesis therapy with bevacizumab as maintenance treatment in a patient with small cell lung cancer:A case report and literature review
Author(s):
Xue Peng12Zhou Lei2Li Linlu1Xu Pengpeng1Wang Ningjun2Wang Fang2Zhu Shijie2
1.Beijing University of Chinese Medicine,Beijing 100029,China;2.Department of Oncology,Wangjing Hospital,China Academy of Chinese Medical Sciences,Beijing 100102,China.
Keywords:
extensive stage small cell lung cancerbevacizumabsurvival time
PACS:
R734.2
DOI:
10.3969/j.issn.1672-4992.2019.03.013
Abstract:
Objective:To investigate the effect of bevacizumab on the progression-free survival and overall survival of patients with extensive stage small cell lung cancer.Methods:We reported a case with 5 cycles of chemotherapy combined bevacizumab and 8 cycles of bevacizumab maintained therapy,and review the relevant literature.Results:The patient achieved 10 months progression-free survival.Conclusion:Bevacizumab for the treatment of extensive small cell lung cancer can prolong progression-free survival and prolong survival.

References:

[1]Riaz SP,Luchtenborg M,Coupland VH,et al.Trends in incidence of small cell lung cancer and all lung cancer[J].Lung Cancer,2012,75(3):280-284.
[2]Chen W,Zheng R,Baade PD,et al.Cancer statistics in China,2015[J].Ca A Cancer Journal for Clinicians,2016,66(2):115.
[3]Kalemkerian GP,Akerley W,Bogner P,et al.Small cell lung cancer[J].Natl Compr Canc Netw,2013,11:78-98.
[4]Howlader N,Noone AM,Krapcho M,et al.Previous version SEER cancer statistics review,1975-2010[R/OL].[2013-6-14].https://seer.cancer.gov/archive/csr/1975__2010/.
[5]Noda K,Nishiwaki Y,Kawahara M,et al.Irinotecan plus cisplatin compared with etoposide plus cisplatin for extensive small-cell lung cancer[J].N Engl J Med,2002,346(2):85-91.
[6]Hermes A,Bergman B,Bremnes R,et al.Irinotecan plus carboplatin versus oral etoposide plus carboplatin in extensive small-cell lung cancer:A randomized phase Ⅲ trial[J].J Clin Oncol,2008,26(26):4261-4267.
[7]Han D,Wang G,Sun L,et al.Comparison of irinotecan/platinum versus etoposide/platinum chemotherapy for extensive-stage small cell lung cancer:A Meta-analysis[J].European Journal of Cancer Care,2017,26(264-269):e12723.
[8]Hanna N,Bunn PJ,Langer C,et al.Randomized phase Ⅲ trial comparing irinotecan/cisplatin with etoposide/cisplatin in patients with previously untreated extensive-stage disease small-cell lung cancer[J].J Clin Oncol,2006,24(13):2038-2043.
[9]Lara PJ,Natale R,Crowley J,et al.Phase Ⅲ trial of irinotecan/cisplatin compared with etoposide/cisplatin in extensive-stage small-cell lung cancer:Clinical and pharmacogenomic results from SWOG S0124[J].J Clin Oncol,2009,27(15):2530-2535.
[10]Lima JP,Dos SL,Sasse EC,et al.Camptothecins compared with etoposide in combination with platinum analog in extensive stage small cell lung cancer:Systematic review with Meta-analysis[J].J Thorac Oncol,2010,5(12):1986-1993.
[11]Schiller JH.Current standards of care in small-cell and non-small-cell lung cancer[J].Oncology,2001,61(Suppl 1):3-13.
[12]Zhou H,Zeng C,Wei Y,et al.Duration of chemotherapy for small cell lung cancer:A Meta-analysis[J].PLoS One,2013,8(8):e73805.
[13]Ferrara N,Gerber HP,Lecouter J.The biology of VEGF and its receptors[J].Nat Med,2003,9(6):669-676.
[14]Lucchi M,Mussi A,Fontanini G,et al.Small cell lung carcinoma(SCLC):The angiogenic phenomenon[J].Eur J Cardiothorac Surg,2002,21(6):1105-1110.
[15]Stefanou D,Batistatou A,Arkoumani E,et al.Expression of vascular endothelial growth factor(VEGF)and association with microvessel density in small-cell and non-small-cell lung carcinomas[J].Histol Histopathol,2004,19(1):37-42.
[16]Sandler A,Gray R,Perry MC,et al.Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer[J].N Engl J Med,2006,355(24):2542-2550.
[17]Cremolini C,Loupakis F,Antoniotti C,et al.FOLFOXIRI plus bevacizumab versus FOLFIRI plus bevacizumab as first-line treatment of patients with metastatic colorectal cancer:Updated overall survival and molecular subgroup analyses of the open-label,phase 3 TRIBE study[J].Lancet Oncol,2015,16(13):1306-1315.
[18]Ruan G,Ye L,Liu G,et al.The role of bevacizumab in targeted vascular endothelial growth factor therapy for epithelial ovarian cancer:An updated systematic review and Meta-analysis[J].Onco Targets Ther,2018,11:521-528.
[19]Horn L,Bernardo P,Sandler A,et al.A phase Ⅱ study of paclitaxel+etoposide+cisplatin+concurrent radiation therapy for previously untreated limited stage small cell lung cancer(E2596):A trial of the Eastern Cooperative Oncology Group[J].J Thorac Oncol,2009,4(4):527-533.
[20]Spigel DR,Greco FA,Zubkus JD,et al.Phase Ⅱ trial of irinotecan,carboplatin,and bevacizumab in the treatment of patients with extensive-stage small-cell lung cancer[J].J Thorac Oncol,2009,4(12):1555-1560.
[21]Spigel DR,Townley PM,Waterhouse DM,et al.Randomized phase Ⅱ study of bevacizumab in combination with chemotherapy in previously untreated extensive-stage small-cell lung cancer:Results from the SALUTE trial[J].J Clin Oncol,2011,29(16):2215-2222.
[22]Ready NE,Dudek AZ,Pang HH,et al.Cisplatin,irinotecan,and bevacizumab for untreated extensive-stage small-cell lung cancer:CALGB 30306,a phase Ⅱ study[J].J Clin Oncol,2011,29(33):4436-4441.
[23]Pujol JL,Lavole A,Quoix E,et al.Randomized phase Ⅱ-Ⅲ study of bevacizumab in combination with chemotherapy in previously untreated extensive small-cell lung cancer:Results from the IFCT-0802 trialdagger[J].Ann Oncol,2015,26:908-914.
[24]Tiseo M,Boni L,Ambrosio F,et al.Italian,multicenter,phase Ⅲ,randomized study of cisplatin plus etoposide with or without bevacizumab as first-line treatment in extensive-disease small-cell lung cancer:The GOIRC-AIFA FARM6PMFJM trial[J].J Clin Oncol,2017,35(12):1281-1287.

Memo

Memo:
-
Last Update: 2018-12-29