|Table of Contents|

Related factors of grade IV myelosupression of patients with solid tumor after chemotherapy

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2019 01
Page:
111-116
Research Field:
Publishing date:

Info

Title:
Related factors of grade IV myelosupression of patients with solid tumor after chemotherapy
Author(s):
Gao YanJiang Qi'anLi JingguoWang Wenming
Department of Oncology,Anqing Hospital Affiliated to Anhui Medical University,Anhui Anqing 246003,China.
Keywords:
solid tumorchemotherapygrade Ⅳ myelosupressionrisk factors
PACS:
R730.5
DOI:
10.3969/j.issn.1672-4992.2019.01.028
Abstract:
Objective:To study the related risk factors of grade Ⅳ myelosupression of patients with solid tumor after conventional dosage chemotherapy.Methods:Collect the clinical data of 94 patients with solid tumor after conventional dosage chemotherapy,among whom,43 developed grade Ⅳ myelosupression,and 51 developed grade 0-Ⅱ myelosupression,to study the related risk factors of grade Ⅳ myelosupression and prophylactico-therapeutic measures.Results:The number of metastatic sites,the number of chemotherapy and the level of myelosupression occur in previous chemotherapy is independent risk factors of grade Ⅳ myelosupression(P=0.002,0.002,0.001 respectively).Subset analyses showed these three factors also is independent risk factors of grade Ⅳ leukocytopenia(P=0.008,0.030,0.001 respectively).Conclusion:Giving prophylactico-therapeutic measures and close follow-up to the patients who with more number of metastatic sites、more number of chemotherapy and severe level of myelosupression occur in previous chemotherapy can help prevent the happeness of grade Ⅳ myelosupression.

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Last Update: 2018-11-30