［1］Boyce BF，Xing L.Functions of RANKL/RANK/OPG in bone modeling and remodeling［J］.Archives of Biochemistry & Biophysics，2008，473(2)：139-146.
[2]Fisher JL，Thomas-Mudge RJ，Elliott J，et al.Osteoprotegerin overexpression by breast cancer cells enhances orthotopic and osseous tumor growth and contrasts with that delivered therapeutically［J］.Cancer Research，2006，66(7)：3620-3628.
[3]D'oronzo S，Brown J，Coleman R.The role of biomarkers in the management of bone-homing malignancies［J］.Journal of Bone Oncology，2017，9：1-9.
[4]Owen S，Sanders AJ，Mason MD，et al.Importance of osteoprotegrin and receptor activator of nuclear factor kappaB in breast cancer response to hepatocyte growth factor and the bone microenvironment in vitro［J］.International Journal of Oncology，2016，48(3)：919-928.
[5]Chung ST，Geerts D，Roseman K，et al.Osteoprotegerin mediates tumor-promoting effects of interleukin-1beta in breast cancer cells［J］.Molecular Cancer，2017，16(1)：27.
[6]Ney JT，Juhasz-boess I，Gruenhage F，et al.Genetic polymorphism of the OPG gene associated with breast cancer［J］.BMC Cancer，2013，13：40.
[7]Kiesel L，Kohl A.Role of the RANK/RANKL pathway in breast cancer［J］.Maturitas，2016，86：10-16.
[8]Park HR，Min SK，Cho HD，et al.Expression of osteoprotegerin and RANK ligand in breast cancer bone metastasis［J］.Journal of Korean Medical Science，2003，18(4)：541-546.
[9]Onyia JE，Galvin RJ，Ma YL，et al.Novel and selective small molpecule stimulators of osteoprotegerin expression inhibit bone resorption［J］.The Journal of Pharmacology and Experimental Therapeutics，2004，309(1)：369-379.
[10]Moran O，Zaman T，Eisen A，et al.Serum osteoprotegerin levels and mammographic density among high-risk women［J］.Cancer Causes Control,2018，29(6)：507-517.
[11]Boudot C，Henaut L，Thiem U，et al.Overexpression of a functional calcium-sensing receptor dramatically increases osteolytic potential of MDA-MB-231 cells in a mouse model of bone metastasis through epiregulin-mediated osteoprotegerin downregulation［J］.Oncotarget，2017，8(34)：56460-56472.
[12]Goswami S，Sharma-Walia N.Osteoprotegerin rich tumor microenvironment：Implications in breast cancer［J］.Oncotarget，2016，7(27)：42777-42791.
[13]Makarovic S，Makarovic Z，Bilic-curcic I，et al.Serum osteoprotegerin in patients with calcified aortic valve stenosis in relation to heart failure［J］.Acta Clinica Croatica，2017，56(4)：733-741.