|Table of Contents|

The effects of Qigui capsule combined with Mannatide Tablets in transcatheter arterial chemoembolization therapy of hepatic rectal cancer metastases in elderly people and its influence on the immune function

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2018 06
Page:
902-907
Research Field:
Publishing date:

Info

Title:
The effects of Qigui capsule combined with Mannatide Tablets in transcatheter arterial chemoembolization therapy of hepatic rectal cancer metastases in elderly people and its influence on the immune function
Author(s):
Liu Chunjun1; Yang Zhe2
1.Department of Pharmacy;2.Department of Radiation Therapy,Central Hospital of Baoji,Shaanxi Baoji 721008,China.
Keywords:
Qigui capsule; mannatide tablets; transcatheter arterial chemoembolization; hepatic rectal cancer metastases
PACS:
R735.3+7
DOI:
10.3969/j.issn.1672-4992.2018.06.021
Abstract:
Objective:To investigate the clinical effects of the effects of qigui capsule combined with mannatide tablets in transcatheter arterial chemoembolization(TACE) therapy of hepatic rectal cancer metastases in elderly people.Methods:From January 2014 to January 2016,82 elderly patients with hepatic rectal cancer metastases treated in ourhospital were randomly divided observation group(41 cases) and control group(41 cases).The patients were treated by TACE and mannatide tablets,while the observation group was given Qigui capsule.After treatment,the curative effects were evaluated in the two groups.The long-term effects were evaluated by observe the 1 year survival rate,2 year survival rate,OS,TTP in the two groups.The levels of CD3+,CD4+,CD8+ and CD19+ in the two groups before and after the treatment were detected.Then the toxicity of the two groups was compared.Results:The total effective rate was 70.7% in the observation group,higher than the 51.2% in the control group(P＜0.05).The 1 year survival rate of observation group was similar with the control group(P＞0.05),while 2 year survival rate,OS and TTP were 58.5%,16.9 months and 11.3 months,significantly higher than which in the control group(P＜ 0.05).The levels of CD3+,CD4+,CD8+ and CD19+ in the observation group were significantly higher than which in the control group(P＜0.05).There were no serious toxicity occurred during the treatment in the two groups and the rates of toxicity were lower in the observation group than the control group(P＜0.05).Conclusion:Qigui capsule combined with mannatide tablets in transcatheter arterial chemoembolization therapy of hepatic rectal cancer metastases in elderly people has a good effect and worth to the next study.

References:

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Memo

Memo:
陕西省自然科学基金资助项目（编号：2012JZ4003）
Last Update: 2018-01-29