|Table of Contents|

Clinicopathological characteristic and prognosis analysis of young patients with colorectal cancer

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2018 06
Page:
888-892
Research Field:
Publishing date:

Info

Title:
Clinicopathological characteristic and prognosis analysis of young patients with colorectal cancer
Author(s):
Xiong Qimin1; Yan Wenyue2; Hu Jing1; Yang Mi1; Li Li1; Liu Baorui1; Qian Xiaoping1
1.The Comprehensive Cancer Center, Nanjing Drum Tower Hospital，The Affiliated Hospital of Nanjing University Medical School，Jiangsu Nanjing 210008，China;2.The Comprehensive Cancer Center，Nanjing Drum Tower Hospital Clinical College of Traditional Chinese
Keywords:
colorectal cancer; young; SEER; clinicopathological characteristics; prognosis
PACS:
R735.3+7
DOI:
10.3969/j.issn.1672-4992.2018.06.018
Abstract:
Objective:The incidence of colorectal cancer(CRC) in young patients(≤40 years of age) appears to be increasing.However,their clinicopathological characteristics and survival are controversial.This study was to compare the characteristics of colorectal cancer in different age group in order to understand the characteristics and prognosis of CRC in young patients.Methods:We collected primary colorectal cancer patients from Nanjing Drum Tower Hospital from January 2011 to December 2015,and Surveillance,Epidemiology,and End Results program from January 2011 to December 2013.All patients were classified into two groups:The young group(≤40 years of age),and the elderly group(> 40 years of age).The characteristics and prognosis of the two groups were compared.Results:A total of 97 369 CRC patients were included from our hospital and the SEER database.The young CRC patients tended to be at rectum and left colon,later stage,more mucinous carcinoma,poorer differentiation,more lymph nodes metastasis,more distant metastasis,higher vessel and nerve invasion.The cancer-specific survival(CCS) of young CRC patients was significantly better.Conclusion：Young CRC patients present advanced tumors and more malignant pathological features,while they have a better prognosis.

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Memo

Memo:
江苏省自然基金（编号：BK20161107）；南京市科技发展计划项目（编号：201503013）
Last Update: 2018-01-29