|Table of Contents|

The application investigation of functional neuronavigation in glioma resection in frontal and parietal lobes

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2018 04
Page:
512-515
Research Field:
Publishing date:

Info

Title:
The application investigation of functional neuronavigation in glioma resection in frontal and parietal lobes
Author(s):
Du Changwang; Shi Luoning; Wang Maode; Chen Wei; Jiang Haitao; Wang Wei; Wang Juan; Mao Ping; Qi Lei
Department of Neurosurgery，First Affiliated Hospital of Xi'an Jiaotong University,Shaanxi Xi'an 710061,China.
Keywords:
glioma in frontal and parietal lobes; BOLD-fMRI; DTI-FT; neuronavigation; intraoperation waking-up; protection of motor function
PACS:
R739.41
DOI:
10.3969/j.issn.1672-4992.2018.04.007
Abstract:
Objective:To explore the clinical value of motor function protection of functional neuronavigation and intraoperative waking-up anesthesia combined with cortical stimulation in glioma resection in frontal and parietal lobes.Methods:157 patients received frontal or parietal glioma resection were separated into two groups randomly.Navigation group of 91 patients using BOLD-fMRI combined with DTI-FT neuronavigation to remove tumor,waking-up group of 66 patients using intraoperative anesthesia combined with cortical electrical stimulation to remove tumor.Results:Results of motor function protection are no difference between navigation group and waking-up group（P＞0.05）.Results of tumor resection ratio are differences between navigation group and waking-up group（P＜0.05）.Results of operation duration are differences between waking-up group and navigation group（P＜0.05）.Conclusion:Both of BOLD-fMRI combined with DTI-FT neuronavigation and intraoperative waking-up anesthesia combined with cortical electrical stimulation showed motor function protective effect in frontal and parietal glioma resections.There was no difference between them,while BOLD-fMRI combined with DTI-FT neuronavigation has higher tumor resection ratio and shorter operation duration than intraoperative waking-up anesthesia combined with cortical electrical stimulation in frontal and parietal glioma resections.Further,it improves the quality of life of patients,so,it is worth to broader implementation.

References:

[1]Wang ZC.Wang Zhongcheng's Neurosurgery［M］.Wuhan:Hubei Science & Technology Press,2005:125-126.［王忠诚.王忠诚神经外科学［M］.武汉:湖北科学技术出版社,2005:125-126.］
[2] Bai HM,Wang WM,Liang S,et al.Modern surgical strategy for eloquent areas［J］.J Clin Neurosurgery,2011,8(5):245-248.［白红民,王伟民,梁树,等.脑功能区胶质瘤的现代手术策略［J］.临床神经外科杂志,2011,8(5):245-248.］
[3]Nossek E,Matot I,Shahar T,et al.Failed awake craniotomy:A retrospective analysis in 424 patients undergoing craniotomy for brain tumor［J］.J Neurosurg,2013,118（2):243-249.
[4]Kumar A,Chandra PS,Sharma BS,et al．The role of neuronavigation-guided functional MRI and diffusion tensor tractography along with cortical stimulation in patients with eloquent cortex lesions［J］.British Journal of Neurosurgery,2014,28(2):226.
[5]Orringer DA，Golby A，Jolesz F．Neumnavigation in the surgical management of brain tumors：Current and future trends［J］.Expert Rev Med Devices,2012,9(5)：491-500.
[6]Mercier L,Del Maestro RF,Petrecca K,et al.New prototype neuronavigation system based on preoperative imaging and intraoperative freehand ultrasound:System description and validation［J］.International Journal of Computer Assisted Radiology and Surgery,2011,6(4):507-522.
[7]Senti C,Forster MT,Bink A,et al.Optimizing the extent of resection in eloquently located gliomas by combining intraoperative MRI guidance with intraoperative neumphysiological monitoring［J］.J Neurooneol,2012,109(1)：81-90．
[8]Yao S,Zhou DS,Dang JT.Microsurgical treatment of meningiomas near the brain under neuronavigation:A report of 30 cases［J］.Shaanxi Medical Journal,2015,44(3):346-347.［姚胜,周东升,党俊涛.神经导航下大脑镰旁脑膜瘤显微手术治疗30例［J］.陕西医学杂志,2015,44(3):346-347.］
[9]Pang CH,Yan J,Long J,et al.Application of 3.0 T mobile iMRI and neuronavigation in the microsurgical operation for the high grade gliomas in brain functional area［J］.Chin J Microsurg,2015,38(4)：323-327.［庞长河,阎静,龙江,等.3.0 T移动iMRI联合导航在显微切除脑功能区高级别胶质瘤手术中的应用［J］.中华显微外科杂志,2015,38(4)：323-327.］
[10]Zhang YH,Liu HY,Zhang R,et al.Application of multimodal neurological imaging and neurophysiological monitoring in surgical resection for eloquently located cerebral gliomas［J］.J Clin Neurosurgery,2016,13(5):335-339.［张玉海,刘宏毅,张锐,等.多模态影像联合电生理监测在脑功能区胶质瘤手术中的应用研究［J］.临床神经外科杂志,2016,13(5):335-339.］
[11]Yu LY,Chen YK,Wang J,et al.Application of neuronavigation multimodal fusing combining intraoperative electrophysiological techniques in the tumor surgery of brain motor areas［J］.Chin J Neurosurg,2016,32(5):443-447.［余龙洋,陈玉坤,汪剑,等.神经导航多模态融合在大脑运动区肿瘤手术中的应用［J］.中华神经外科杂志,2016,32(5):443-447.］
[12]Lu T,Feng M,Cui G,et al.The application of navigation with magnetic resonance diffusion tensor imaging in glioma surgery of brain functional area［J］.Guangdong Medical Journal,2016,37(15):2275-2277.［陆挺,冯鸣,崔岗,等.磁共振弥散张量成像示踪神经纤维束结合神经导航在脑功能区胶质瘤手术中的应用［J］.广东医学,2016,37(15):2275-2277.］

Memo

Memo:
National Natural Science Foundation of China（No.81602207）；国家自然科学基金资助项目（编号：81602207）
Last Update: 2017-12-29