|Table of Contents|

The observation of therapeutic efficacy of sequential chemo-radiation therapy combined with Lienal Polypeptide Injection in treating limited and advanced non-small cell lung cancer

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2018 02
Page:
201-204
Research Field:
Publishing date:

Info

Title:
The observation of therapeutic efficacy of sequential chemo-radiation therapy combined with Lienal Polypeptide Injection in treating limited and advanced non-small cell lung cancer
Author(s):
Miao Shuanlin; Li Wei; Li Renshuan; Miao Manyuan
Xianyang Hospital of Yan'an University,Shaanxi Xianyang 721000,China.
Keywords:
non-small cell lung cancer; sequential chemo-radiation therapy; Lienal Polypeptide Injection; KPS score
PACS:
R734.2
DOI:
10.3969/j.issn.1672-4992.2018.02.011
Abstract:
Objective:To investigate the therapeutic efficacy of Lienal Polypeptide Injection combined with sequential chemo-radiation therapy in treating limited and advanced non-small cell lung cancer.Methods:A total of 84 patients with limited and advanced non-small cell lung cancer were randomly divided into observation group（42 cases) and control group（42 cases).Patients in the observation group were administrated with Lienal Polypeptide Injections when undergoing sequential chemo-radiation therapy,while patients in the control group were given only sequential chemo-radiation therapy.The general situation,clinical efficacy,side effectsand effect on T lymphocyte subsets of both groups were observed after therapy.Results:After therapy,the average KPS value in patients of the observation group was higher than control group（89.66±7.4 vs 80.24±6.8,P＜0.05).The rate of efficiency and control in two groups were both no significant difference（P＞0.05).The rate of hematologic toxicity and infection in the observation group was significantly lower than that control group（P＜0.05).The observation group of T cell subgroup analysis the immune indexes was also significantly better than that of control group（P＜0.05).Conclusion:During sequential chemo-radiation therapy,the addition of Lienal Polypeptide Injection will improve the general condition and the quality of life,reduce side effects of patients with limited and advanced non-small cell lung cancer,which is an effective treatment and worths further clinical application.

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Last Update: 2017-11-30