|Table of Contents|

Current management of peripheral T-cell lymphomas

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2018 01
Page:
158-161
Research Field:
Publishing date:

Info

Title:
Current management of peripheral T-cell lymphomas
Author(s):
Zhou XuemengHe YanxiaQu TongZhang Yue
Department of Medical Oncology,the Affiliated Tumor Hospital of Harbin Medical University,Heilongjiang Harbin 150081,China.
Keywords:
PTCLshistone deacetylase inhibitorsproteasome inhibitorsimmunotherapy
PACS:
R733.4
DOI:
Abstract:
Peripheral T-cell lymphomas (PTCLs) are an uncommon group of lympho-proliferative disorders,accounting for approximately 10%~15% of all non-Hodgkin's lymphomas (NHL).PTCLs' prognosis is vary with disease subtype.The standard of care is anthracycline-based induction combination chemotherapy.Consolidation with autologous stem cell transplantation is usually recommended for patients.However,with the exception of flow-risk ALK-positive anaplastic large cell lymphoma (ALCL),relapse rates are high.In recent years,a number of novel agents including pralatrexate,histone deacetylase inhibitors,proteasome inhibitors,have shown promise in the treatment of PTCLs.This article will summarize current management of PTCL in recent years.

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黑龙江省自然科学基金重点项目(编号:ZD2016018)
Last Update: 2017-11-30