|Table of Contents|

Discussion and analysis of the radiation field design in the treatment of the middle-thoracic esophageal cancer

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2017 06
Page:
942-944
Research Field:
Publishing date:

Info

Title:
Discussion and analysis of the radiation field design in the treatment of the middle-thoracic esophageal cancer
Author(s):
Chen Li; Tan Fei; Wu Wenjuan; Jiang Yaqi
Department of Oncology,Northern Jiangsu People's Hospital,Jiangsu Yangzhou 225001,China.
Keywords:
esophageal cancer; IMRT; OARs; prescription dose
PACS:
R735.1
DOI:
10.3969/j.issn.1672-4992.2017.06.029
Abstract:
Objective:To compare the dosimetric difference of several 3D IMRT treatments of the middle-thoracic esophageal carcinoma.Methods:The data of 65 cases of esophageal cancer were selected,and four radiotherapy plans were designed for each patient.The first plan,0°,72°,144°,216°,288°,The second plan,0°,50°、150°,210°,310°,The third plan,0°,51°,102°,153°,204°,255°,306°,The fourth plan,0°,40°,80°,120°,160°,200°,240°,280°,320°,Compare the dosimetric differences of the four methods of target organ and crisis.Results:Four IMRT plans can cover the target area D95.Four plans on the dosimetric differences were not statistically significant,about OARs,The second plan was obvious advantages in the lung dosimetry by comparing of Dmean,V5,V10.Heart radiation dose was higher,but there was no statistical difference.In the spinal cord dose is also relatively high,but there is no statistical difference.Conclusion:In the same target area of the same prescription dose,the five fields unequal division plan can effectively reduce the exposure dose of the lung.

References:

［1］Nutting CM,Bedford JL,Cosgrove VP,et al.A comparison of conformal and intensity-modulated techniques for esohpageal radiotherapy［J］.Radiother Oncol,2001,61(2):157-163.
［2］Ishikura S,Nihei K,Ohtsu A,et al.Long-term toxicity after definitive chemoradiotherapy for squamous cell carcinoma of the thoracic esophagus［J］.J Clin Oncol,2003,21(14):2697-2702.
［3］Pignol JP，Olivotto I，Rakovitch E，et al．A multicenter randomized trial of breast intensity-modulated radiation therapy to reduce acute radiation dermatitis［J］．J Clin Oncol，2008，26(13)：2085-2092．
［4］Yu Changhua，Wang Wanwei，Zhu Weiguo，et al．SIB-IMRT for neck and upper thoracic esophageal carcinoma［J］．China Res Preventi Treat，2010，37(5)：575-577．
［5］Morton LM，Gilbert ES，Hall P，et al.Risk of treatment-related esophageal cancer among breast cancer survivors［J］.Annals Oncology，2012，23(12):3081-3091.
［6］Tanabe S，Myojin M，Shimizu S，et al.Dose-volume analysis for respiratory toxicity in intrathoracic esophageal cancer patients treated with definitive chemoradiotherapy using extended fields［J］.J Radiation Res，2013，54(6):1085-1094.
［7］Sun Ronggang.Esophageal twice radiotherapy compared with radiotherapy efficacy of fusion single［J］.Modern Oncology，2014，22（2)：337-339.［孙荣刚.食管癌两次放疗计划融合与单次放疗计划疗效比较［J］.现代肿瘤医学，2014，22(2):337-339.］
［8］Shi Liwan,Fu Lirong,Ha Huiming,et al.Dosimetric comparison of three dimentional conformal radiotherapy and intensity modulated radiotherapy for middle thoracic esophageal cancer definitive radiotherapy［J］.Chinese Journal of Medical Physics,2012,29(1):3104-3107.［石丽婉,傅丽蓉,哈晦明,等.胸中段食管癌根治性放疗三维适形放疗与调强放疗剂量学比较［J］.中国医学物理学杂志,2012,29(1):3104-3107.］
［9］Fakhrian K,Oechsner M,Kampfer S,et al.Advanced techniques in neoadjuvant radiotherapy allow dose escalation without increased dose to the organs at risk［J］.Strahlenther Onkol,2013,189(4):293-300.
［10］Wang SL,Liao Z,Vaporciyan AA,et al.Investigation of clinical and dosimetric factors associated with postoperative pulmonary complications in escophageral cancer patients treated with concurrent chemoradiotherapy followed by surgery［J］.Int J Radiat Oacol Bio Phys,2006,64(3):692-699.
［11］Ge Xiuhong,Li Qianwen.The chose and apply of radiotherapy technologies in esophageal cancer［J］.Modern Oncology,2015,23（5）:695-698.［葛秀红,李前文.食管癌放射治疗技术的选择与应用［J］.现代肿瘤医学,2015,23（5）:695-698.］

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扬州市科技计划项目（编号：YZ2014181）
Last Update: 2017-01-26