|Table of Contents|

Prognostic factors of brain metastases in patients with colorectal cancer

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2017 06
Page:
918-920
Research Field:
Publishing date:

Info

Title:
Prognostic factors of brain metastases in patients with colorectal cancer
Author(s):
Cao Shuqin; Duan Lixia
Department of Oncology,Qinghai Red Cross Hospital,Qinghai Xining 810000,China.
Keywords:
colorectal cancer; brain metastasis; prognosis
PACS:
R735.3
DOI:
10.3969/j.issn.1672-4992.2017.06.021
Abstract:
Objective:To explore the related factors of colorectal cancer patients with brain metastases.Methods:According to the treatment method patients were divided into experimental group and the control group.Results:The mean survival time of patients in the experimental group,1-year survival rate,3-year survival and 5-year survival rate were better than the control group (P＜0.05).Logistic regression analysis showed that gender,primary tumor histological grade were not prognostic factors in patients with brain metastases.Colorectal cancer with brain metastasis related factors were primary tumor diameter,number of brain metastases,serum CEA level,treatment methods,the treatment of brain metastases.Logistic stepwise regression analysis showed that serum CEA levels on prognosis maximum (OR=3.743),the number of brain metastases (OR=3.153),treatment (OR=2.946),age (>60 years) (OR=1.900).Conclusion:The factors affecting the prognosis of patients with brain metastases of colorectal cancer were primary tumor diameter,number of foci of brain metastases,serum CEA level,treatment methods,the treatment of brain metastases or not,and age.

References:

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Last Update: 2017-01-26