|Table of Contents|

The research status of keratinocyte growth factor and its receptor in the gynecological cancer

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2017 05
Page:
833-836
Research Field:
Publishing date:

Info

Title:
The research status of keratinocyte growth factor and its receptor in the gynecological cancer
Author(s):
Li Zheng12Chen Yu12Wang Zhenguo12
1.Hebei North University,Hebei Zhangjiakou 075000,China;2.The 309th Hospital of PLA,Beijing 100091,China.
Keywords:
gynecological cancerkeratinocyte growth factor receptor(KGFR)cervical cancerendometrial cancer
PACS:
R737.3
DOI:
10.3969/j.issn.1672-4992.2017.05.044
Abstract:
There is no molecular detective targets in diagnosis of gynecologic tumors that have unified and clear standards.Although people always have the hope to find a newly detective target in numerous detected factors,which could be more effective in disease diagnosis,prognosis and treatment,detecting squamous cell carcinoma antigen still is a common use for cervical cancer.Keratinocyte growth factor and its receptor have been found different performance in many kinds of tumors,and related to their occurence and development.This article mainly demonstrates the detected evolvement and current research progress of keratinocyte growth factor and its receptor in the growth of gynecological tumors.

References:

[1]Rubin JS,Osada H,Finch PW,et al.Purification and characterization of a newly identified growth factor specific for epithelial cells[J].Proc Natl Acad Sci USA,1989,86(3):802-806.
[2]Li X,Liang L,Zhao P,et al.The effects of adenoviral transfection of the Keratinocyte growth factor gene on epidermal stem cells:an in vitro study[J].Mol Cells,2013,36(4):316-321.
[3]Marti GP,Mohebi P,Liu L,et al.KGF-1 for wound healing in animal models[J].Methods Mol Biol,2008,423:383-391.
[4]Shyamsundar M,McAuley DF,Ingram RJ,et al.Keratinocyte growth factor promotes epithelial survival and resolution in a human model of lung Injury[J].Am J Respir Crit Care Med,2014,189(12):1520-1529.
[5]Toriseva M,Ala-aho R,Peltonen S,et al.Ketratinocyte growth factor induces gene expression signature associated with suppression of malignant phenotype of cutaneous squamous carcinoma cells[J].PLoS One,2012,7(3):e33041.
[6]Tani H,Saito N,Kobayashi M,et al.Clinical significance of keratinocyte growth factor and K-sam gene expression in gastric cancer[J].Mol Med Rep,2013,7(5):1381-1386.
[7]Amano R,Yamada N,Doi Y,et al.Significance of Keratinocyte growth factor receptor in the proliferation of biliary tract cancer[J].Anticancer Res,2010,30(10):4115-4121.
[8]Ishikawa A,Kudo M,Nakazawa N,et al.Expression of keratinocyte growth factor and its receptor in human endometrial cancer in cooperation with steroid hormones[J].Int J Oncol,2008,32(3):565-574.
[9]Masunaga A,Nagashio R,Iwamoto S,et al.A case of pulmonary papillary adenoma:Possible relationship between tumor histogenesis/tumorigenesis and fibroblast growth factor receptor 2 IIIb[J].Pathol Int,2012,62(9):640-645.
[10]Finch PW,Rubin JS.Keratinocyte growth factor expression and activity in cancer:implications for use in patients with solid tumors[J].J Natl Cancer Inst,2006,98(12):812-824.
[11]Kesinger JW,Mehta M,Lerner MR,et al.Oncolytic potential of a novel KGFR tyrosine kinase inhibitor using a KGFR-selective breast cancer xenograft model[J].Anticancer Res,2015,35(1):47-52.
[12]Rotolo S,Ceccarelli S,Romano F,et al.Silencing of Keratinocyte growth factor receptor restores 5-fluorouracil and tamoxifen efficacy on responsive cancer cells[J].PLoS One,2008,3(6):e2528.
[13]Lu L,Li YH,Du XQ,et al.Expression of KGFR in cervical cancer tissues and action of KGFR on proliferation of the Hela,CaSki cells[J].West China Medical Journal,2008,23(6):1339-1340.[陆琳,李燕华,杜晓琴,等.KGFR在宫颈癌组织中的表达及对Hela、CaSki细胞增殖的影响[J].华西医学,2008,23(6):1339-1340.]
[14]Kurban G,Ishiwata T,Kudo M,et al.Expression of keratinocyte growth factor receptor(kgfrfgfr iiib)in human uterine cervical cancer[J].Oncol Rep,2004,11(5):987-991.
[15]Hatila·Jingsihan,Meiliban·Tuerxun,Ma H,et al.Expression of KGFR and P16INK4a protein in Xinjiang Uygur women cervical intraepithelial neoplasia and cervical cancer[J].J Xinjiang Med University,2011,34(2):147-150.[哈提拉·京斯汗,美力班·吐尔逊,马红,等.KGFR、P16(INK4a)在新疆维吾尔族妇女宫颈上皮内瘤变及宫颈癌中的表达及意义[J].新疆医科大学学报,2011,34(2):147-150.]
[16]Zhang YJ,Lalai·Suzuke.Expression and significance of KGF、P16 in the diagnosis of cervical in-traepithel neoplasia and cervixcar cinoma[J].J Clin Exp Pathol,2007,23(6):727-728.[张亚静,拉莱·苏祖克.子宫颈上皮内瘤变及子宫颈鳞癌中KGF、p16表达及意义[J].临床与实验病理学杂志,2007,23(6):727-728.]
[17]Lu L,Wang D,Hu LN,et al.Expression and action of keratinocyte growth factor,keratinocyte growth factor receptor on CaSki cell[J].J Sichuan Univ (Med Sci Edi),2007,38(5):836-838.[陆琳,王东,胡丽娜,等.角质细胞生长因子及其受体在CaSki细胞中的表达及其作用[J].四川大学学报(医学版),2007,38(5):836-838.]
[18]Lu L,Hu LN,Li SQ,et al.Expression and action of keratinocyte growth factor,keratinocyte growth factor receptor on HeLa cell[J].J Sichuan Univ (Med Sci Edi),2007,38(3):437-439.[陆琳,胡丽娜,李双庆,等.角质细胞生长因子及其受体在HeLa细胞中的表达及其作用[J].四川大学学报(医学版),2007,38(3):437-439.]
[19]Siegfried S,Pekonen F,Nyman T,et al.Expression of mRNA for keratinocyte growth factor and its receptor in human endometrium[J].Acta Obstet Gynecol Scand,1995,74(6):410-414.
[20]Koji T,Chedid M,Rubin JS,et al.Progesterone-dependent expression of keratinocyte growth factor mRNA in stromal cells of the primate endometrium:keratinocyte growth factor as progestomedin[J].J Cell Biol,1994,125(2):393-401.
[21]Siegfried S,Pekonen F,Nyman T,et al.Distinct patterns of expression of keratinocyte growth factor and its receptor in endometrial carcinoma[J].Cancer,1997,79(6):1166-1171.
[22]Visco V,Carico E,Marchese C,et al.Expression of keratinocyte growth factor receptor compared with that of epidermal growth factor receptor and erbB-2 in endometrial adenocarcinoma[J].Int J Oncol,1999,15(3):431-435.
[23]Taniguchi F,Harada T,Sakamoto Y,et al.Activation of mitogen-activated protein kinase pathway by keratinocyte growth factor or fibroblast growth factor-10 promotes cell proliferation in human endometrial carcinoma cells[J].J Clin Endocrinol Metab,2003,88(2):773-780.
[24]Pekonen F,Nyman T,Rutnen EM.Differential expression of keratinocyte growth factor and its receptor in the human uterus[J].Mol Cell Endocrino,1993,195(1-2):43-49.
[25]Taniguchi F,Harada T,Iwabe T,et al.Aberrant expression of keratinocyte growth factor receptor in ovarian surface epithelial cells of endometrioma[J].Fertil Steril,2008,89(2):478-480.
[26]Guo L,Yang W,Ye SQ,et al.Effect of keratinocyte growth factor on cell invasion and migration in epithelial ovarian cancer cell lines[J].J Harbin Mei,2013,47(5):388-391.[郭 玲,杨薇薇,叶盛前,等.角质细胞生长因子在卵巢癌细胞增殖和侵袭中的作用[J].哈尔滨医科大学学报,2013,47(5):388-391.]
[27]Wang XH,Li JJ.Effect of keratinocyte growth factor on proliferation of CAOV 3cells and activity of ERK[J].Shandong Med J,2006,46(24):5-6.[汪向红,李晶晶.KGF对人卵巢癌CAOV3细胞增殖及其ERK活性的影响[J].山东医药,2006,46(24):5-6.]
[28]Taniguchi F,Harada T,Ito M,et al.Keratinocyte growth factor in the promotion of human chorionic gonadotropin production in human choriocarcinoma cells[J].Am J Obstet Gynecol,2000,182(3):692-698.
[29]Ding F,Wu XY,Niu B,et al.The effect of KGF on proliferation and secretion of JEG -3 and BeWo choriocarnoma cells in vitro[J].Prac J Med & Pharm,2008,25(11):1362-1364.[丁峰,吴晓英,钮彬,等.KGF对绒癌细胞系JEG-3及BeWo体外增殖和分泌功能的影响[J].实用医学杂志,2008,25(11):1362-1364.]
[30]Ding F,Niu B,Zheng YQ.Effects of KGF/KGFR in the malignant transformation of hydatidiformmole[J].Med J Chin PLA,2008,38(7):850-856.[丁峰,钮彬,郑煜清.角质细胞生长因子及其受体在葡萄胎恶性变中的作用[J].解放军医学杂志,2008,38(7):850-856.]

Memo

Memo:
-
Last Update: 2017-01-26