|Table of Contents|

The expression of AKAP4 in colon cancer and its clinical pathological significance

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2017 03
Page:
422-424
Research Field:
Publishing date:

Info

Title:
The expression of AKAP4 in colon cancer and its clinical pathological significance
Author(s):
Zi Yonghong1Ji Le1Chen Hongmei2Zhang Runqi3Zhou Yi3
1.Department of General Surgery,Affiliated Hospital of Medical College,Yan'an University,Shaanxi Yan'an 716099,China;2.Yan'an Vocational and Technical College,Shaanxi Yan'an 716099,China;3.Department of Pathology,Xi'an Medical University,Shaanxi Xi'an 710021,China.
Keywords:
AKAP4colon cancerimmunohistochemical
PACS:
R739.3+5
DOI:
10.3969/j.issn.1672-4992.2017.03.021
Abstract:
Objective:To explore the expression of AKAP4 in colon cancer and analyze the relationship between AKAP4 and the clinical pathological parameter of colon cancer.Methods:A total of 80 cases of colon cancer and 30 cases of normal colon epithelium were collected.The expression of AKAP4 was measured by immnohistochemistry.Results:The positive expression rate of AKAP4 in tumor tissues was 76.3%,significantly higher than that in normal colon epithelium.Positive expression of AKAP4 was not correlated with age,gender,differentiation and lymph node metastasis,only correlated with stage.Conclusion:AKAP4 is overexpressed in colon cancer tissue,and it is correlated with stage.It may be involved in colon cancer progression,and is considered as a therapeutic strategy in colon cancer.

References:

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Memo

Memo:
陕西省自然科学基础研究计划项目(编号:2013JM4054)
Last Update: 2016-12-29