|Table of Contents|

Efficacy of Kanglaite CHPP combined with XELOX chemotherapy on patients with progressive gastric cancer

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2017 02
Page:
266-269
Research Field:
Publishing date:

Info

Title:
Efficacy of Kanglaite CHPP combined with XELOX chemotherapy on patients with progressive gastric cancer
Author(s):
Li MinghuiLiu HongboFeng Yunzhang
The Second Department of General Surgery,Handan Central Hospital,Hebei Handan 056001,China.
Keywords:
continuous hyperthermic peritoneal perfusioncombination therapyKanglaiteXELOXprogressive gastric cancer
PACS:
R735.2
DOI:
10.3969/j.issn.1672-4992.2017.02.028
Abstract:
Objective:To investigate the clinical effect and security of Kanglaite CHPP for patients with progressive gastric cancer.Methods:All patients were divided into two groups randomly.32 patients were underwent general CHPP combined with chemotherapy by XELOX while the other group of 31 patients were treated by Kanglaite CHPP combined with chemotherapy by XELOX.Results:After 2 years,the local relapse rate was 32.3% in experimental group and 46.9% in control group(P<0.05).The hepatic metastasis rate was also significantly lower in experimental group than in control group(12.9% vs 34.4%,P<0.05).After 3 years,the relapse rate in experimental group was still lower than that in control group(41.9% vs 65.6%,P<0.05),and the same situation was observed in the hepatic metastasis rate(22.6% vs 43.8%,P<0.05).There was no significant difference in the adverse reactions between two groups.Conclusion:Kanglaite CHPP combined with chemotherapy by XELOX may be a safe and effective therapy for the patients with progressive gastric cancer,be helpful for preventing recurrence and can prolong survival time.

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Last Update: 2016-12-01