|Table of Contents|

Rsf-1/HBXAP expression and its significance in common digestive system tumor

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2017 01
Page:
151-154
Research Field:
Publishing date:

Info

Title:
Rsf-1/HBXAP expression and its significance in common digestive system tumor
Author(s):
Yang Le1; Liu Jintao2
1.Graduate School of Guangdong Medical University，Guangdong Zhanjiang 524000，China；2.Digestive System Department，Baoan People's Hospital of Shenzhen，Guangdong Shenzhen 518101，China.
Keywords:
Rsf-1; digestive system; tumor; expression
PACS:
R730.5
DOI:
10.3969/j.issn.1672-4992.2017.01.041
Abstract:
Chromatin remodeling factor 1(remodeling and spacing factor 1，Rsf-1；also known as hepatitis B X-antigen associated protein，HBXAP)，located in 11q13.5，belong to the human core protein and chromatin assembly related factor is a member of the family，it's a to promote cancer gene，the study found that in breast cancer，gastric cancer，colorectal cancer，lung cancer，hepatocellular carcinoma，ovarian cancer，and also so，high expression in the tumor tissure and have a great relationship with the prognosisof patients.Knockdown Rsf-1 gene expression and corresponding joint application anti-cancer drugs may become the tumor treatment strategy.Rsf-1 high expression in tumor tissue of cases，the clinical prognosis worse than lower expression Rsf-1.Rsf-1 in the early days of digestive system tumors sensitivity is higher than other tumor markers，whether can be used as the best markers for early diagnosis of digestive system tumors remains to be further research.

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Memo

Memo:
深圳市宝安区医疗卫生科研立项项目(编号： 2016CX168）
Last Update: 2016-12-01