|Table of Contents|

Correlation of serum VEGF,TNF-α,IL-6 and prognosis of patients with esophageal cancer

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2017 01
Page:
63-66
Research Field:
Publishing date:

Info

Title:
Correlation of serum VEGF,TNF-α,IL-6 and prognosis of patients with esophageal cancer
Author(s):
Hu JinhuaZhang YaoqingZhu Bin
The Second Department of General Surgery,Jingshan People's Hospital of Hubei Province,Hubei Jingshan 431899,China.
Keywords:
esophageal cancerTNF-αIL-6VEGFtumor staginglymphatic metastasis
PACS:
R735.1
DOI:
10.3969/j.issn.1672-4992.2017.01.017
Abstract:
Objective:To investigate the correlation of serum TNF-α,IL-6,VEGF and patients with differentiated esophageal cancer invasion and metastasis.Methods:Serum levels of TNF-α,IL-6 and VEGF were quantified by ELISA on 128 cases of differentiated esophageal cancer (esophageal cancer group),84 cases of esophageal leiomyoma (esophageal leiomyoma group),and 80 healthy people (control group).Results:The serum concentrations of TNF-α,IL-6 and VEGF in esophageal cancer were higher than leiomyoma of esophagus group and control group (P<0.01).Concentrations of TNF-α,IL-6 and VEGF were higher in stage IV> stage III> stage I and II.Comparing with no lymphatic metastasis group,with lymphatic metastasis group was higher has statistical significance (P<0.01).Conclusion:The serum levels of TNF-α,IL-6 and VEGF have positive correlation to the invasion and metastasis of differentiated esophageal cancer.There is of great significance of TNF-α,IL-6 and VEGF serum levels for estimating the progression and prognosis of patients with esophageal cancer.

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Last Update: 2016-12-01