|Table of Contents|

Research progress on the correlation between obesity and lung cancer

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2025 06
Page:
1034-1038
Research Field:
Publishing date:

Info

Title:
Research progress on the correlation between obesity and lung cancer
Author(s):
HUANG Ling; ZHAO Mingdong; MOU Xiang; QU Xiaoyan; LEI Jiawen
The Second People's Hospital Affiliated to Three Gorges University,Three Gorges University Endoscopic Minimally Invasive Medical Research Institute,Yichang Second People's Hospital,Hubei Yichang 443000,China.
Keywords:
obesity; lung cancer; BMI; the obesity paradox
PACS:
R734.2
DOI:
10.3969/j.issn.1672-4992.2025.06.021
Abstract:
Obesity and lung cancer are important public health issues that have attracted global attention.Although obesity has been identified as an important risk factor for various cancers such as esophageal cancer,breast cancer,and colon cancer,the relationship between obesity and lung cancer remains unclear.Most previous studies have suggested that obesity is not associated with lung cancer,and even has a certain protective effect.Obesity is associated with the use of drugs,smoking,obesity measurement methods,immune disorders and other confounding factors,resulting in this paradox.Due to the limitations of body mass index (BMI) in measuring obesity,it cannot accurately describe the distribution of body fat and cannot distinguish between fat and muscle content,which masks the potential impact of obesity on lung cancer patients.This hazard becomes apparent when obesity is measured as visceral obesity.In particular,the risk of lung cancer increased significantly when visceral obesity combined with low BMI,which is helpful to identify the high risk population of lung cancer.In clinical work,the selection of accurate obesity measurement methods and the timely assessment of the health status of patients will also provide a new direction for the prevention and treatment of lung cancer.The aim of this article is to analyze the factors leading to obesity paradox and its impact on lung cancer,and to further elaborate the correlation between obesity and lung cancer.

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湖北省重点实验室开放基金（编号：2017KZL02）
Last Update: 1900-01-01