|Table of Contents|

Research progress and prospects on immunotherapy of extensive-stage small cell lung cancer

Journal Of Modern Oncology[ISSN:1672-4992/CN:61-1415/R]

Issue:
2025 06
Page:
1024-1033
Research Field:
Publishing date:

Info

Title:
Research progress and prospects on immunotherapy of extensive-stage small cell lung cancer
Author(s):
MA Yongchun1XIE Yujin2ZHOU Yawen3MA Huan3MA Long34ZHU Zijiang3
1.Xining First People's Hospital,Qinghai Xining 810000,China;2.The 4th People's Hospital of Qinghai Province,Qinghai Xining 810000,China;3.Department of Thoracic Surgery,Gansu Provincial Central Hospital(Gansu Province Maternity and Child Health Hospital)
Keywords:
extensive-stage small-cell lung cancerimmunotherapyresearch progress
PACS:
R734.2
DOI:
10.3969/j.issn.1672-4992.2025.06.020
Abstract:
Small cell lung cancer is a malignant tumor with high degree of malignancy,fast growth rate and poor prognosis.About 70% of patients with small cell lung cancer have been in the extensive stage at the first diagnosis.For a long time,the treatment of small cell lung cancer has been stagnant.In recent years,immunotherapy has made new breakthroughs in small cell lung cancer.Clinical trials of some immune checkpoint inhibitors have confirmed the effectiveness and safety of small cell lung cancer.This article reviews the clinical progress of programmed death protein-1 (PD-1)/programmed death ligand-1 (PD-L1) inhibitors and cytotoxic T lymphocyte antigen-4 (CTLA-4) inhibitors in the treatment of extensive-stage small cell lung cancer.

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Memo

Memo:
National Natural Science Foundation of China(No.3176050013);国家自然科学基金项目(编号:3176050013)
Last Update: 1900-01-01